{"id":830545,"date":"2026-08-30T05:54:16","date_gmt":"2026-08-30T05:54:16","guid":{"rendered":"https:\/\/www.newsbeep.com\/us\/830545\/"},"modified":"2026-08-30T05:54:16","modified_gmt":"2026-08-30T05:54:16","slug":"nocebo-effect-is-the-placebos-evil-twin","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us\/830545\/","title":{"rendered":"Nocebo effect is the placebo&#8217;s evil twin"},"content":{"rendered":"<p>In late 2022, as the fentanyl drug overdose epidemic raged across America, police officers making street busts of the synthetic opioid began experiencing what they believed were \u201clife-threatening\u201d reactions.<\/p>\n<p>In Florida, an officer lost consciousness after touching a powder she thought was fentanyl. She felt \u201clight-headed \u2026 I was choking. I couldn\u2019t breathe,\u201d the officer told a local Florida TV station.<\/p>\n<p>Her department blamed her frightening reaction on fentanyl exposure. <\/p>\n<p>Some police officers involved in fentanyl busts have wrongly thought they were feeling the effects of the drug.  AFP via Getty Images<\/p>\n<p>In Ohio, the arresting officer in a fentanyl case who discovered a \u201cspeck\u201d of white powder on his sweatshirt suddenly became disoriented and unsteady on his feet. He\u00a0told BuzzFeed News at the time that he\u00a0remembered \u201cpanicking, trying to talk,\u201d and then falling.<\/p>\n<p>NYPD cops were not immune.<\/p>\n<p>In 2024, during a fentanyl bust in a Bronx apartment, two responding officers suddenly became ill. <\/p>\n<p>EMS was called as fumes from the lids holding the drug filled the apartment. One cop was treated at the scene; the other at St. Barnabas Hospital.<\/p>\n<p>Again, fentanyl was blamed.<\/p>\n<p>But, \u201cthings are not quite what they seem,\u201d\u00a0writes Dr. Helen Pilcher in \u201c<a data-aps-asc-tag=\"nypost-20\" data-aps-asin=\"1419774662\" data-wrapped-template=\"https:\/\/r.nypostlink.com?btn_ref=org-19984c113c692001&amp;btn_url\" href=\"https:\/\/r.nypostlink.com?btn_ref=org-19984c113c692001&amp;btn_url=https%3A%2F%2Fwww.amazon.com%2FThis-Book-Cause-Side-Effects%2Fdp%2F1419774662%2F%3Ftag%3Dnypost-20%26asc_refurl%3Dhttps%3A%2F%2Fnypost.com%2F2026%2F08%2F29%2Fhealth%2Fnocebo-effect-is-the-placebos-evil-twin%2F%26asc_source%3Dweb\" target=\"_blank\" rel=\"nofollow noopener\">This Book May Cause Side Effects: Why Our Minds Are Making Us Sick<\/a>\u201d (Abrams Press, out now). There is a \u201cmisplaced belief\u201d among cops, Pilcher notes, that \u201cfentanyl can do this \u2026 is strong enough [in minute quantities] to skew the brain\u2019s prediction machinery and cause \u2026 frightening symptoms.\u201d<\/p>\n<p>But, the author asserts that the officers \u201cdid not overdose at all. They had functional seizures. They collapsed because they expected to collapse.\u201d\u00a0<\/p>\n<p>A new book by Helen Pilcher explores the nocebo effect. <\/p>\n<p>Pilcher writes that these instances are prime examples of \u201cthe nocebo effect,\u201d which she describes as \u201cthe placebo effect\u2019s evil twin, night to its day, yin to its yang, Hyde to its Jekyll.\u201d<\/p>\n<p>When people wrongly attribute positive health outcomes \u2014 like a headache subsiding or a cough quelling \u2014 to a useless sugar pill, it\u2019s a placebo effect.<\/p>\n<p> When they wrongly believe they have been exposed to something toxic, contagious or otherwise harmful and feel poorly, it\u2019s a nocebo. <\/p>\n<p>\u00a0\u201cWhen people are warned to expect symptoms, they become more likely to experience them,\u201d Pilcher writes. \u201cPositive expectations lead to positive health outcomes. Symptoms improve, illness fades,\u201d while \u201cdark expectations can sometimes spawn truly dark realities.\u201d<\/p>\n<p>She cites the instance of a patient in Nashville, Tennessee, who died of esophageal cancer after doctors told him the cancer had spread and there was nothing more they could do.<\/p>\n<p>\u201cWhen people are warned to expect symptoms, they become more likely to experience them,\u201d Pilcher writes Tuan  Nguyen  \u2013 stock.adobe.com<\/p>\n<p>The autopsy showed no evidence of widespread cancer. Files had been mixed up and the poor man had been given another patient\u2019s diagnosis. <\/p>\n<p>\u201cThe doctor\u2019s words were as effective as poison,\u201d Pilcher writes. <\/p>\n<p>In Germany during COVID, some people developed symptoms\u00a0like chronic jaw pain, fatigue and shortness of breath\u00a0overnight after watching a YouTuber talking about his case.<\/p>\n<p>Pilcher believes the viewers\u2019 symptoms were generated through subconscious processes in the brain.<\/p>\n<p>The World Health Organization also noted that media coverage on the spread of COVID and its symptoms led many to feel ill even though they didn\u2019t actually have the virus.<\/p>\n<p>The World Health Organization has noted that media coverage on the spread of COVID and its symptoms led many to feel ill even though they didn\u2019t actually have the virus. Photocreo Bednarek \u2013 stock.adobe.com<\/p>\n<p>The nocebo effect has been around for at least 200,000 years, according to Pilcher. Throughout history, there have been instances of hex deaths \u2014 people dying after they believed they\u2019d been cursed by some powerful authority.\u00a0<\/p>\n<p>In 1857, Portuguese naturalist Gabriel Soares de Sousa wrote of how, while exploring South America, he witnessed men die after being cursed by a medicine man.<\/p>\n<p>Three hundred years later, a Brazilian historian corroborated the story that when they were told to die by a medicine man \u2014 they did.<\/p>\n<p>Physiologist Walter Cannon from Harvard Medical School coined the term \u201cvoodoo death\u201d in 1942, writing that psychological threats can trigger a physical one. The adrenaline rush, initially helpful, can become toxic.<\/p>\n<p>Living through a pandemic, an earthquake, or a shaman\u2019s voodoo curse increases the risk of a fatal heart attack \u2014 \u201can ominous and persistent state of fear can end the life of a person,\u201d Cannon wrote.<\/p>\n<p>In recent years, social media has exacerbated the nocebo effect, \u201cturbocharging the spread of nocebo-generated symptoms.\u201d<\/p>\n<p>Pilcher advises people to be wary of turning to Doctor Google or looking to TikTok for medical advise.<\/p>\n<p>\u201cIf you have symptoms and you are worried, go see a\u00a0real\u00a0doctor\u201d and \u201cchoose that doctor carefully, because all doctors are not created equal,\u201d she writes. \u201cOur experience of illness is heavily influenced by the world around us, by the thoughts we have towards different ailments and by the expectations we have of our bodies to deal with them.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"In late 2022, as the fentanyl drug overdose epidemic raged across America, police officers making street busts of&hellip;\n","protected":false},"author":2,"featured_media":830546,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[34],"tags":[223,6883,11983,97,42337,5599],"class_list":["post-830545","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-books","tag-coronavirus","tag-fentanyl","tag-health","tag-postscript","tag-public-health"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/830545","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/comments?post=830545"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/830545\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media\/830546"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media?parent=830545"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/categories?post=830545"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/tags?post=830545"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}