{"id":840583,"date":"2026-09-08T12:42:14","date_gmt":"2026-09-08T12:42:14","guid":{"rendered":"https:\/\/www.newsbeep.com\/us\/840583\/"},"modified":"2026-09-08T12:42:14","modified_gmt":"2026-09-08T12:42:14","slug":"study-suggests-ai-generated-drug-could-slow-aging","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us\/840583\/","title":{"rendered":"Study Suggests AI-Generated Drug Could Slow Aging"},"content":{"rendered":"

An AI-generated drug showed early signs of potentially slowing aging, according to a new study<\/a> out today in Nature Biotechnology, possibly taking the first small step towards using AI to cure all the diseases tech companies companies keep talking about.<\/p>\n

The new study centers on rentosertib, a drug from Insilico Medicine<\/a>, an AI drug discovery and development company. From the onset, Insilico said it created<\/a> rentosertib with the aim of both treating patients suffering chronic lung disease and extending their lifespan. In the study<\/a>, the company showed that its drug managed to successfully reduce some of the biological markers of age, as measured by aging clocks, in a small set of patients.<\/p>\n

Aging clocks have moved from a sort of shorthand to a reference of where a person is in their life (\u201ctheir biological clock is ticking\u201d) to a real metric\u00a0that aims to measure a person\u2019s morbidity and mortality. A number of these clocks have been developed with AI to take many measurements\u2014biomarkers in blood, physiological metrics, psychological assessments, etc.\u2014and spit out a biological \u201cage\u201d meant to reflect a person\u2019s overall health.<\/p>\n

In the 42 participants of the study, Insilico found that its drug managed to reduce their biological ages over the course of the 12-week trial, while those who received a placebo or no treatment saw their age increase or stay the same. The company used six different so-called aging clocks and noticed enough of a shift on all six to conclude that \u201cthe drug may modulate complementary dimensions of biological aging.\u201d<\/p>\n

The idea of reducing aging certainly sounds good (and has become the obsession of some tech bro-types<\/a>), but the actual utility of aging clocks is up for debate.<\/p>\n

There are several variations of these clocks, all of which take different approaches. The earliest versions, developed over a decade ago, track methylation<\/a>, which observes chemical changes in DNA. More recent models focus on proteomics, or measuring blood proteins, which a 2024 study<\/a> found could be used to determine if a person had a higher risk of age-related diseases.<\/p>\n

And while some researchers believe that these catch-all measurements could be useful<\/a>, there\u2019s still a long way to go before they become truly meaningful markers. Scientists have tried to kick-start the field and improve accuracy<\/a> so that such tools can be used for research purposes, but there still isn\u2019t a measurement that serves as a universally accepted \u201cage\u201d indicator\u2014and some doctors have warned that leaning on these metrics could lead to pursuing the wrong interventions<\/a>, seeking ways to slow aging indicators in a way that actually harms a body\u2019s repair response.<\/p>\n

All that said, a pill that keeps a person\u2019s body from succumbing to the effects of aging would be a breakthrough. Insilico\u2019s pill is still a long way from being that\u2014it\u2019ll have lot of trials to go before getting any sort of regulatory approval.<\/p>\n","protected":false},"excerpt":{"rendered":"An AI-generated drug showed early signs of potentially slowing aging, according to a new study out today in…\n","protected":false},"author":2,"featured_media":840584,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[34],"tags":[2594,24620,1873,97],"class_list":["post-840583","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-aging","tag-artifical-intelligence","tag-generative-ai","tag-health"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/840583","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/comments?post=840583"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/840583\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media\/840584"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media?parent=840583"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/categories?post=840583"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/tags?post=840583"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}