{"id":858233,"date":"2026-09-23T21:54:10","date_gmt":"2026-09-23T21:54:10","guid":{"rendered":"https:\/\/www.newsbeep.com\/us\/858233\/"},"modified":"2026-09-23T21:54:10","modified_gmt":"2026-09-23T21:54:10","slug":"cellares-snuh-partner-on-cell-therapy-manufacturing","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us\/858233\/","title":{"rendered":"Cellares, SNUH Partner on Cell Therapy Manufacturing"},"content":{"rendered":"<p><a href=\"https:\/\/www.contractpharma.com\/company-profile\/cellares\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Cellares<\/a> has entered a collaboration with <a href=\"https:\/\/www.snuh.org\/global\/en\/main.do\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Seoul National University Hospital<\/a> (SNUH) to evaluate automated manufacturing for SNUH\u2019s gene-modified hematopoietic stem and progenitor cell therapy for paroxysmal nocturnal hemoglobinuria (PNH).<\/p>\n<p>The proof-of-concept work will focus on transferring SNUH\u2019s manufacturing process to <a href=\"https:\/\/www.contractpharma.com\/breaking-news\/cellares-completes-first-cgmp-compliant-cell-shuttle\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Cellares\u2019 Cell Shuttle platform<\/a>, including a two-step transfection workflow supported by Cellares\u2019 fully integrated, single-use electroporation module.<\/p>\n<p>The agreement is Cellares\u2019 second collaboration in Asia and expands the company\u2019s presence in the Asia-Pacific region. Cellares said the program is intended to support preclinical development and IND-enabling manufacturing as SNUH advances the therapy toward future clinical development in the U.S.<\/p>\n<p>SNUH is developing gene-modified hematopoietic stem cell therapies in collaboration with global institutions. The partners aim to establish a scalable manufacturing strategy for the PNH program using automated, closed-system manufacturing.<\/p>\n<p>\u201cAdvancing gene-modified HSPC therapies requires a manufacturing approach that can support both the complexity of the process and the rigor of clinical translation,\u201d said Professor Youngil Koh, Director of the SNUH GMP Facility. \u201cBy working with Cellares, we are evaluating how automation can strengthen manufacturing reliability and scalability as we advance this program toward clinical development.\u201d<\/p>\n<p>\u201cGene-modified HSPC therapies are a natural fit for the Cell Shuttle and an area where Cellares has established manufacturing expertise,\u201d said Fabian Gerlinghaus, Co-Founder and CEO of Cellares. \u201cBy automating complex workflows, including electroporation, we can deliver the scalability, reliability and manufacturing economics required to advance these therapies through clinical development. This partnership extends that capability to SNUH as it prepares its PNH program for future clinical development in the United States.\u201d<\/p>\n<p>Gene-modified HSC manufacturing remains labor-intensive, variable and difficult to scale, which can limit clinical development, increase manufacturing costs and constrain patient access. Cellares says the Cell Shuttle is designed to automate end-to-end cell therapy manufacturing and improve scalability and reliability for autologous cell therapy programs.<\/p>\n","protected":false},"excerpt":{"rendered":"Cellares has entered a collaboration with Seoul National University Hospital (SNUH) to evaluate automated manufacturing for SNUH\u2019s gene-modified&hellip;\n","protected":false},"author":2,"featured_media":858234,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[4,450,451,3,452,453],"class_list":["post-858233","post","type-post","status-publish","format-standard","has-post-thumbnail","category-breaking-news","tag-breaking-news","tag-breakingnews","tag-headlines","tag-news","tag-top-stories","tag-topstories"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/858233","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/comments?post=858233"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/858233\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media\/858234"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media?parent=858233"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/categories?post=858233"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/tags?post=858233"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}