{"id":887124,"date":"2026-10-19T00:02:09","date_gmt":"2026-10-19T00:02:09","guid":{"rendered":"https:\/\/www.newsbeep.com\/us\/887124\/"},"modified":"2026-10-19T00:02:09","modified_gmt":"2026-10-19T00:02:09","slug":"one-blood-type-seems-to-carry-a-higher-risk-of-type-2-diabetes-sciencealert","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/us\/887124\/","title":{"rendered":"One Blood Type Seems to Carry a Higher Risk of Type 2 Diabetes : ScienceAlert"},"content":{"rendered":"<p class=\"wp-block-paragraph\">Depending on your blood type, it&#8217;s possible you could carry a higher  <a href=\"https:\/\/www.sciencealert.com\/diabetes\" class=\"lar_link lar_link_outgoing\" data-linkid=\"73018\" data-postid=\"224660\" rel=\"nofollow noopener\" target=\"_self\">diabetes<\/a> risk, research suggests.<\/p>\n<p class=\"wp-block-paragraph\">According to a <a href=\"https:\/\/doi.org\/10.1186\/s12916-024-03423-x\" rel=\"nofollow noopener\" target=\"_blank\">2024 review<\/a>, people with blood type B \u2013 either positive or negative \u2013 face a slightly higher risk of developing <a href=\"https:\/\/www.sciencealert.com\/scientists-think-theyve-found-a-new-cause-of-type-2-diabetes\" rel=\"nofollow noopener\" target=\"_blank\">type 2 diabetes<\/a> than people with non-B blood types.<\/p>\n<p class=\"wp-block-paragraph\">How much higher?<\/p>\n<p class=\"wp-block-paragraph\">About 28 percent, on average. That might not seem huge, but it may be significant enough to tip the scales if other risk factors are involved.<\/p>\n<p class=\"wp-block-paragraph\">&#8220;Numerous systematic reviews with meta-analyses have been published, which explored correlations between ABO and Rhesus blood groups with various health outcomes,&#8221; <a href=\"https:\/\/doi.org\/10.1186\/s12916-024-03423-x\" rel=\"nofollow noopener\" target=\"_blank\">wrote a team<\/a> led by epidemiologist Fang-Hua Liu of Shengjing Hospital of China Medical University.<\/p>\n<p class=\"wp-block-paragraph\">&#8220;However, to date, the association between these blood groups and human health outcomes remains controversial. The current umbrella review included 51 systematic reviews with  <a href=\"https:\/\/www.sciencealert.com\/meta-analysis\" class=\"lar_link lar_link_outgoing\" data-linkid=\"73088\" data-postid=\"224660\" rel=\"nofollow noopener\" target=\"_self\">meta-analysis<\/a> articles with 270 associations.<\/p>\n<p class=\"wp-block-paragraph\">&#8220;We recalculated each association and found only one [instance of] convincing evidence for an association between blood group B and type 2 diabetes mellitus risk compared with the non-B blood group.&#8221;<\/p>\n<\/p>\n<p class=\"wp-block-paragraph\">Human blood is categorized into <a href=\"https:\/\/www.lifeblood.com.au\/donors\/blood-plasma-platelets\/learn\/blood\/blood-types\" rel=\"nofollow noopener\" target=\"_blank\">eight main groups<\/a> based on the sugars and proteins, or lack thereof, present on the surface of your red blood cells.<\/p>\n<p class=\"wp-block-paragraph\">A, B, and AB types are based on the presence of antigens \u2013 sugar molecules that can trigger an immune response. O-type blood has no A or B antigens. Meanwhile, Rhesus (Rh) factors are proteins that determine blood compatibility and give your blood its positive or negative designation.<\/p>\n<p class=\"wp-block-paragraph\">Previous studies have suggested that these subtle differences in our blood cells may be linked to <a href=\"https:\/\/doi.org\/10.7554\/eLife.83116\" rel=\"nofollow noopener\" target=\"_blank\">increased vulnerability to certain diseases<\/a>.<\/p>\n<p class=\"wp-block-paragraph\">Liu and colleagues embarked on their study to systematically evaluate links between blood type and disease across a catalog of around 270 different health outcomes.<\/p>\n<p class=\"wp-block-paragraph\">A <a href=\"https:\/\/doi.org\/10.1093\/aje\/kwae232\" rel=\"nofollow noopener\" target=\"_blank\">systematic review<\/a> is a study that reviews published papers on a given topic and analyzes their results collectively. An <a href=\"https:\/\/bmjmedicine.bmj.com\/content\/1\/1\/e000071\" rel=\"nofollow noopener\" target=\"_blank\">umbrella review<\/a> compiles systematic reviews \u2013 a sort of giant synthesis that provides a wider overview.<\/p>\n<p class=\"wp-block-paragraph\">Think of individual studies as trees; a systematic review is like standing outside a copse, while an umbrella review is like flying a drone over a whole forest of copses.<\/p>\n<p><img decoding=\"async\" width=\"642\" height=\"413\" src=\"https:\/\/www.newsbeep.com\/us\/wp-content\/uploads\/2026\/10\/MajorBloodTypesChart642.jpg\" alt=\"Blood Type Details\" class=\"wp-image-177480\"   loading=\"lazy\"\/>Blood type (or blood group) is determined, in part, by the ABO blood group antigens present on red blood cells.  <a href=\"https:\/\/www.sciencealert.com\/antibody\" class=\"lar_link lar_link_outgoing\" data-linkid=\"73081\" data-postid=\"224660\" rel=\"nofollow noopener\" target=\"_self\">Antibodies<\/a> in our blood plasma detect when a foreign antigen marker is present. (<a href=\"https:\/\/commons.wikimedia.org\/wiki\/File:ABO_blood_type.svg\" rel=\"nofollow noopener\" target=\"_blank\">InvictaHOG\/Wikimedia Commons<\/a>, public domain)<\/p>\n<p class=\"wp-block-paragraph\">&#8220;We systematically searched PubMed, Web of Science, Embase, Scopus, Cochrane Library, and several regional databases on the date from inception until Feb 16, 2024, to identify systematic reviews with meta-analyses of observational studies evaluating associations between ABO as well as Rh blood groups and diverse health outcomes,&#8221; <a href=\"https:\/\/doi.org\/10.1186\/s12916-024-03423-x\" rel=\"nofollow noopener\" target=\"_blank\">the researchers explained<\/a>.<\/p>\n<p class=\"wp-block-paragraph\">To sort through the 270 reported links between blood group and disease, the researchers put each one through a series of statistical stress tests designed to weed out weak or unreliable findings.<\/p>\n<p class=\"wp-block-paragraph\">They examined the strength of the evidence, whether results were consistent across different studies, and whether the datasets were large enough to be trustworthy.<\/p>\n<p class=\"wp-block-paragraph\">They also checked for signs of bias, such as small studies exaggerating effects or an unusually high number of positive results.<\/p>\n<p class=\"wp-block-paragraph\">Crucially, they asked whether each association would likely hold up if tested again in future research. Most of the associations didn&#8217;t pass these checks.<\/p>\n<p class=\"wp-block-paragraph\">In the end, just one link, between blood type B and type 2 diabetes, met the highest standard of evidence.<\/p>\n<p class=\"wp-block-paragraph\">That suggests that the link is real, albeit relatively small: just 28 percent higher than the current baseline. That&#8217;s much smaller than the risk associated with diet, weight, or lifestyle.<\/p>\n<p class=\"wp-block-paragraph\">Just 50 grams of processed meat a day, for example, increases the risk of type 2 diabetes <a href=\"https:\/\/doi.org\/10.1136\/bmj.l2368\" rel=\"nofollow noopener\" target=\"_blank\">by 37 percent<\/a>. A sedentary lifestyle can increase the risk <a href=\"https:\/\/doi.org\/10.1159\/000357332\" rel=\"nofollow noopener\" target=\"_blank\">by 112 percent<\/a>. And being overweight is one of the <a href=\"https:\/\/doi.org\/10.2337\/dc25-S008\" rel=\"nofollow noopener\" target=\"_blank\">strongest risk factors known<\/a>.<\/p>\n<p class=\"wp-block-paragraph\">The researchers also didn&#8217;t examine what might drive this increased risk. A 2025 study suggests that the <a href=\"https:\/\/doi.org\/10.2337\/db25-1434-P\" rel=\"nofollow noopener\" target=\"_blank\">gut microbiome may be involved<\/a>; however, further investigation is needed.<\/p>\n<p class=\"wp-block-paragraph\">The results do suggest that there&#8217;s a real, tangible association between blood type and type 2 diabetes \u2013 one that people can factor into how they think about their own risk.<\/p>\n<p class=\"wp-block-paragraph\">Still, your blood type alone won&#8217;t make or break your diabetes risk. Diet, activity levels, and weight matter far more \u2013 this is just one more piece of a puzzle scientists are still putting together.<\/p>\n<p class=\"wp-block-paragraph\">The research was published in <a href=\"https:\/\/doi.org\/10.1186\/s12916-024-03423-x\" rel=\"nofollow noopener\" target=\"_blank\">BMC Medicine<\/a>.<\/p>\n<p>This article was fact-checked by <a href=\"https:\/\/www.sciencealert.com\/jess-cockerill\" rel=\"nofollow noopener\" target=\"_blank\">Jess Cockerill<\/a> and edited by <a href=\"https:\/\/www.sciencealert.com\/fiona-macdonald\" rel=\"nofollow noopener\" target=\"_blank\">Fiona MacDonald<\/a>. While we pride ourselves on our process, we are only human. If you spot a mistake, <a href=\"https:\/\/www.sciencealert.com\/contact-us\" rel=\"nofollow noopener\" target=\"_blank\">please let us know<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"Depending on your blood type, it&#8217;s possible you could carry a higher diabetes risk, research suggests. According to&hellip;\n","protected":false},"author":2,"featured_media":887125,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[34],"tags":[97,1352],"class_list":["post-887124","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-health","tag-msft-content"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/887124","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/comments?post=887124"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/887124\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media\/887125"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media?parent=887124"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/categories?post=887124"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/tags?post=887124"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}