A spider, when knocked off a wall, doesn\u2019t fall for long. Within milliseconds, it spins a soup of proteins into sturdy climbing gear. Using a thin, shimmering strand of silk, the spider hauls itself back up.<\/p>\n
The strand is tougher than Kevlar, the synthetic fiber in bike tires and bulletproof vests, and stronger than steel. It\u2019s flexible and biocompatible with human bodies. Scientists dream of making spider silk into high-performing materials for seat belts, helmets, naval materials, and even scaffolds to help repair brain cells. But attempts to make spider silk in the lab have fallen short because researchers don\u2019t know enough about how a spider spins \u201csilk dope,\u201d a liquid blend of proteins, water, and salt, from its silk glands into a remarkable solid.<\/p>\n
Mapping out the molecular mechanisms behind the process is \u201creally the holy grail\u201d for the field, said Gregory Holland<\/a>, a chemist and spectroscopist at San Diego State University. Recently, he led research that described how the molecules in liquid spider dope reorganize into semiliquid droplets called condensates before turning into solid silk fiber. The result is an atomic-level look<\/a> into the spider\u2019s silk factory.<\/p>\n The findings are also a practical guide to the formation of condensates, which nature has used repeatedly to organize molecules for genetic processes and for the creation of impressively strong biological materials.<\/p>\n \u201cIt\u2019s becoming clear that [condensates are] a common strategy that\u2019s being used across a range of different organisms,\u201d said Matthew Harrington<\/a>, a biological materials scientist at McGill University who was not involved in the study. By unpacking how nature uses condensates, scientists hope to re-create some of its most rugged materials.<\/p>\n Silk Factory<\/p>\n Spiders are incredible natural factories. They can spin up to seven types of silks, and the same spider can often spin several of them. Aciniform silk wraps up insects for later snacking. Rubbery flagelliform silk reinforces the capture spiral to absorb shock. Dragline silk anchors webs and spiders to walls. Each type of silk has different properties depending on the species and related to how its molecules are assembled. And silks of the same type can have slightly different properties depending on the species.<\/p>\n In 1907, scientists discovered that spider silk is made of long, modular proteins, later named spidroins, which are in the same group of fiber proteins as collagen and keratin. More than half a century later, X-rays started to reveal the fiber\u2019s underlying structure. The silk is made of flat sheets of protein, known as beta sheets<\/a>, that are embedded in a less ordered, non-crystalline matrix.<\/p>\n","protected":false},"excerpt":{"rendered":"A spider, when knocked off a wall, doesn\u2019t fall for long. Within milliseconds, it spins a soup of…\n","protected":false},"author":2,"featured_media":898048,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[32],"tags":[79],"class_list":["post-898047","post","type-post","status-publish","format-standard","has-post-thumbnail","category-science","tag-science"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/898047","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/comments?post=898047"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/posts\/898047\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media\/898048"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/media?parent=898047"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/categories?post=898047"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/us\/wp-json\/wp\/v2\/tags?post=898047"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}