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Browsing Tag

Aging

212 posts
HHealthcare
Data Holds the Key in Slowing Age-Related Illnesses
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Data Holds the Key in Slowing Age-Related Illnesses

  • December 24, 2025
In 2026, we will see the beginning of precision medical forecasting. Just as there have been remarkable advances…
FFitness
3 Pushup Variations That Prove Strength After 50
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3 Pushup Variations That Prove Strength After 50

  • December 23, 2025
Try this 3-pushup challenge to see how strong your upper body really is after 50. Building upper-body strength…
CCelebrities
Alyssa Milano celebrates 53rd birthday with annual makeup-free selfie
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Alyssa Milano celebrates 53rd birthday with annual makeup-free selfie

  • December 20, 2025
Happy 53rd birthday, Alyssa Milano! Instagram/Alyssa Milano Isn’t she lovely? Actress Alyssa Milano took to Instagram this morning…
FFitness
6 Bodyweight Moves That Support Healthy Aging After 60
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6 Bodyweight Moves That Support Healthy Aging After 60

  • December 19, 2025
Keep your body strong and healthy for years to come by weaving these exercises into your regular routine.…
HHealthcare
Anna Sinaiko.
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Is cost curbing use of weight loss drugs? — Harvard Gazette

  • December 19, 2025
Popular new anti-obesity medications can help people lose 10 to 20 percent of their body weight, yet a…
FFitness
5 Standing Exercises to Tighten Neck and Jawline After 50
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5 Standing Exercises to Tighten Neck and Jawline After 50

  • December 17, 2025
Define your neck and jawline with these easy standing exercises that strengthen and lift. Many changes happen to…
HHealth
Cellular responses to ischemic reperfusion injury in young vs older donor organs. During ischemia, the deprivation of oxygen and nutrients leads to mitochondrial dysfunction and energy loss. In young cells, mitochondrial resilience helps sustain ATP production, ameliorating damage. Old cells, in contrast, experience significant ATP depletion, relying heavily on anaerobic metabolism, which leads to lactate buildup, pH reduction, and cellular stress. Upon reperfusion, the restoration of blood flow triggers oxidative stress as mitochondria generate excessive reactive oxygen species (ROS). Young cells compensate for those events through robust antioxidant systems, maintaining cellular integrity. Conversely, in old cells, impaired antioxidant defenses result in unregulated ROS production, furthermore damaging membranes, organelles, and DNA. Additionally, old cells release pro-inflammatory genes, amplifying local inflammation. Consequences are particularly severe in aged vascular endothelial cells, with ion pump dysfunction (e.g., Na⁺/K⁺ ATPase) causing ionic imbalances and cellular edema. This disruption exacerbates ischemic injury, progressing to irreversible damage. In contrast, young cells effectively resolve edema and inflammation through mechanisms that include macrophage945 mediated clearance of Damage-Associated Molecular Patterns (DAMPs) and anti-inflammatory cytokine release (e.g., IL-10 and TGF-β), allowing recovery and tissue repair. In old cells, persistent ROS generation, unresolved inflammation, and DAMP accumulation lead to irreversible inflammation, organelle collapse, and eventual cell death. Created in BioRender. Kayumov, M. (2025) https://BioRender.com/m23u7ro .
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Scientists outline how organ rejuvenation strategies could solve the donor shortage

  • December 12, 2025
New insights into cellular aging, perfusion technologies, and senescence-targeting treatments show how aging organs could be revived, turning…
NNutrition
Gary Brecka reveals his 6 free biohacks
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Gary Brecka reveals his 6 free biohacks

  • December 10, 2025
You don’t have to be a billionaire to biohack your way to a longer life. “The most powerful…
CCelebrities
Kate Winslet Is Not a Botox Fan
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Kate Winslet Is Not a Botox Fan

  • December 9, 2025
Photo: JC Olivera/WWD via Getty Images Kate Winslet would like everyone to keep their faces au naturel. In…
NNutrition
Diets Rich in Tea, Coffee, Berries and Nuts Linked to Better Long-term Heart Health in New Study
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Diets Rich in Tea, Coffee, Berries and Nuts Linked to Better Long-term Heart Health in New Study

  • December 9, 2025
Credit: Julian Hochgesang People who regularly consume polyphenol-rich foods and drinks, such as tea, coffee, berries, cocoa, nuts,…
FFitness
4 Simple Exercises to Restore Muscle After 60
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4 Simple Exercises to Restore Muscle After 60

  • December 5, 2025
Try these 4 simple moves to rebuild lost muscle and feel stronger and steadier after 60. There’s a…
HHealthcare
Can AI Look at Your Retina and Diagnose Alzheimer’s? Eric Topol Hopes So
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Can AI Look at Your Retina and Diagnose Alzheimer’s? Eric Topol Hopes So

  • December 5, 2025
For decades now, it’s been fairly well established that once you turn 40 you should start paying more…
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