NutriMatch: harmonizing food composition databases with large language models for enhanced nutritional prediction
Data collection We utilized data from the 10K Project, a prospective human cohort study involving over 10,000 healthy…
Twisted graphene puts magnetic fields in check
A graphene-based quantum sensor uses two decoupled layers to form a quantized 4 × 4 Landau-level checkerboard when…
The tolerance-related psychology and dynamic activity in the peripheral nervous system of Internet gaming disorder during playing online games | BioMedical Engineering OnLine
Questionnaire To assess the psychometric variables associated with problematic gaming, we used the CIAS [7], IGDS [8], and…
Barriers to translating continuous monitoring technologies for preventative medicine
What is Diabetes? (CDC, 2023). Harris, M. I. & Eastman, R. C. Early detection of undiagnosed diabetes mellitus:…
MSnLib: efficient generation of open multi-stage fragmentation mass spectral libraries
Materials All solvents used were of LC–MS grade. Methanol, acetonitrile, water and formic acid were obtained from Thermo…
Systema: a framework for evaluating genetic perturbation response prediction beyond systematic variation
Nonparametric baselines We design two nonparametric baselines that we refer to as perturbed mean and matching mean. Perturbed…
CRISPR-GPT for agentic automation of gene-editing experiments
Building AI co-pilot harnessing LLM’s reasoning ability CRISPR-GPT supports four major gene-editing modalities and 22 gene-editing experiment tasks…
Morphological map of under- and overexpression of genes in human cells
Mattiazzi Usaj, M. et al. High-content screening for quantitative cell biology. Trends Cell Biol. 26, 598–611 (2016). CAS …
The Platinum Pedigree: a long-read benchmark for genetic variants
Gonzaga-Jauregui, C., Lupski, J. R. & Gibbs, R. A. Human genome sequencing in health and disease. Annu. Rev.…
Deep-learning-based gene perturbation effect prediction does not yet outperform simple linear baselines
The success of large language models in knowledge representation has spawned efforts to apply the foundation model concept…
GeneAgent: self-verification language agent for gene-set analysis using domain databases
Model setting and data collection In this work, we utilized GPT-4 (version 20230613) as the backend model via…
Single-cell polygenic risk scores dissect cellular and molecular heterogeneity of complex human diseases
Single-cell multiome dataset Single-cell multiome (snRNA-seq + snATAC-seq) data of the human left ventricle and lung were processed and clustered…