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Despite therapeutic advancements, the prognosis for metastatic ccRCC remains poor, with a 5-year survival rate of approximately 12–20…

Abul-Husn, N. S. & Kenny, E. E. Personalized medicine and the power of electronic health records. Cell 177,…

Symmons, O. et al. The Shh topological domain facilitates the action of remote enhancers by reducing the effects…

Gerstein, M. B. et al. Architecture of the human regulatory network derived from ENCODE data. Nature 489, 91–100…

Study design and data sources The data used in this study are collected and used in line with…

Hartwell, L. H., Szankasi, P., Roberts, C. J., Murray, A. W. & Friend, S. H. Integrating genetic approaches…

Kuo, C. F. et al. Global epidemiology of gout: prevalence, incidence and risk factors. Nat. Rev. Rheumatol. 11,…

de Magalhaes, J. P. How ageing processes influence cancer. Nat. Rev. Cancer 13, 357–365 (2013). Article PubMed Google…

Ethics Our study complies with all relevant ethical regulations and was approved by the institutional review boards at…

Enrollment rates Between 28 September 2023 and 10 June 2024 (~8.5 months), a total of 2,125 newborns were enrolled.…

Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This…

Is it possible to treat obesity without reducing food intake? A new study co-led by Dr. Antonio Zorzano…