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Browsing Tag

Cell

259 posts
HHealth
Excessive amounts of visceral fat tied to faster heart aging
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Human heart organoids enable new therapies for atrial fibrillation

  • December 13, 2025
Though an estimated 60 million people around the world have atrial fibrillation, or A-fib, a type of irregular…
HHealth
Excessive amounts of visceral fat tied to faster heart aging
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Nighttime heart attacks cause less damage due to neutrophil circadian rhythms

  • December 13, 2025
Heart attacks that occur at night are less severe than those that strike during the day. A new…
NNutrition
Study: Vitamin B12: A Comprehensive Review of Natural vs Synthetic Forms of Consumption and Supplementation. Image Credit: Fida Olga / Shutterstock
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Why the form of vitamin B12 you take may matter more than your intake

  • December 12, 2025
A new scientific review weighs natural and synthetic forms of vitamin B12, revealing where methylcobalamin may outperform standard…
HHealth
Cellular responses to ischemic reperfusion injury in young vs older donor organs. During ischemia, the deprivation of oxygen and nutrients leads to mitochondrial dysfunction and energy loss. In young cells, mitochondrial resilience helps sustain ATP production, ameliorating damage. Old cells, in contrast, experience significant ATP depletion, relying heavily on anaerobic metabolism, which leads to lactate buildup, pH reduction, and cellular stress. Upon reperfusion, the restoration of blood flow triggers oxidative stress as mitochondria generate excessive reactive oxygen species (ROS). Young cells compensate for those events through robust antioxidant systems, maintaining cellular integrity. Conversely, in old cells, impaired antioxidant defenses result in unregulated ROS production, furthermore damaging membranes, organelles, and DNA. Additionally, old cells release pro-inflammatory genes, amplifying local inflammation. Consequences are particularly severe in aged vascular endothelial cells, with ion pump dysfunction (e.g., Na⁺/K⁺ ATPase) causing ionic imbalances and cellular edema. This disruption exacerbates ischemic injury, progressing to irreversible damage. In contrast, young cells effectively resolve edema and inflammation through mechanisms that include macrophage945 mediated clearance of Damage-Associated Molecular Patterns (DAMPs) and anti-inflammatory cytokine release (e.g., IL-10 and TGF-β), allowing recovery and tissue repair. In old cells, persistent ROS generation, unresolved inflammation, and DAMP accumulation lead to irreversible inflammation, organelle collapse, and eventual cell death. Created in BioRender. Kayumov, M. (2025) https://BioRender.com/m23u7ro .
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Scientists outline how organ rejuvenation strategies could solve the donor shortage

  • December 12, 2025
New insights into cellular aging, perfusion technologies, and senescence-targeting treatments show how aging organs could be revived, turning…
HHealth
Conceptual framework linking ultra-processed foods (UPFs) to mechanistic pathways, inflammatory cascade, clinical outcomes, and dietary interventions in inflammatory bowel disease (IBD).
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How ultra-processed foods shape Crohn’s disease risk and what dietary strategies can really help

  • December 12, 2025
New evidence reveals how everyday processed foods may disrupt gut barriers and amplify inflammation, while targeted dietary strategies…
HHealth
Uncovering the secrets of ‘SuperAgers’ and cognitive longevity
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Researchers identify enzyme linked to myelin damage and neurodegenerative conditions

  • December 12, 2025
Researchers at Oregon Health & Science University have identified a type of enzyme with a complicated name –…
HHealth
New approach doubles chemotherapy effectiveness by targeting cancer cell memory
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AI uncovers how DNA architecture failures trigger blood cancer

  • December 11, 2025
Cancer isn’t just about broken genes-it’s about broken architecture. Imagine a city where roads suddenly vanish, cutting off…
HHealth
Discovery links human M cells to early steps of celiac disease
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Discovery links human M cells to early steps of celiac disease

  • December 11, 2025
The human small intestine absorbs nutrients while protecting us from potentially harmful microbes. One of the cell types…
SScience
Study: Nanomaterial-induced mitochondrial biogenesis enhances intercellular mitochondrial transfer efficiency. Image Credit: Julien Tromeur / Shutterstock
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Nanoflower-treated stem cells deliver healthier mitochondria to stressed cells

  • December 10, 2025
By engineering nanomaterials that boost mitochondrial biogenesis, researchers show how stem cells can become powerful “mitochondrial biofactories,” offering…
HHealth
Study: Dietary iron deficiency impairs effector function of memory T cells following influenza infection. Image Credit: Corona Borealis Studio  / Shutterstock
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Poor dietary iron weakens lung memory T cells after flu infection

  • December 8, 2025
Even when immune memory cells form in the lung after influenza infection, insufficient dietary iron leaves them less…
TTechnology
Extreme morning sickness found to carry heavy emotional and physical burden
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Early pregnancy placenta models show significant effects from PFAS exposure

  • December 5, 2025
Per- and polyfluoroalkyl substances (PFAS) are a group of nearly 10,000 long-lasting chemical compounds that stay in the…
HHealth
Efficacy of methylprednisolone doses in severe Mycoplasma Pneumonia
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Bacterial enzyme linked to heart complications in pneumonia

  • December 5, 2025
Pneumonia is a disease that burdens the healthcare system with more that 1.2 million emergency room visits each…
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