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Browsing Tag

Computational biology and bioinformatics

7 posts
HHealthcare
Reporting guidelines for studies involving generative artificial intelligence applications: what do I use, and when?
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Reporting guidelines for studies involving generative artificial intelligence applications: what do I use, and when?

  • November 8, 2025
The rise in publications addressing the use of general artificial intelligence (GAI), namely large language models (LLMs), for…
HHealthcare
Evaluating GPT-4’s ability to generate informed consent material for genetic testing
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Evaluating GPT-4’s ability to generate informed consent material for genetic testing

  • November 4, 2025
Our findings showed that GPT-4-generated materials for both NIPT and BRCA cases remained difficult to read according to…
GGenetics
Nucleotide dependency analysis of genomic language models detects functional elements
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Nucleotide dependency analysis of genomic language models detects functional elements

  • October 11, 2025
SpeciesLM training For SpeciesLM metazoa, we obtained metazoan genomes comprising 494 different species from the Ensembl 110 database36.…
GGenetics
CellNavi predicts genes directing cellular transitions by learning a gene graph-enhanced cell state manifold
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CellNavi predicts genes directing cellular transitions by learning a gene graph-enhanced cell state manifold

  • October 6, 2025
Input embeddings In CellNavi, we use single-cell raw count matrices as the only input. Specifically, the single-cell sequencing…
GGenetics
Spatial architecture of development and disease
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Spatial architecture of development and disease

  • October 1, 2025
Bressan, D., Battistoni, G. & Hannon, G. J. The dawn of spatial omics. Science 381, eabq4964 (2023). Article …
GGenetics
CRISPR-GPT for agentic automation of gene-editing experiments
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CRISPR-GPT for agentic automation of gene-editing experiments

  • August 13, 2025
Building AI co-pilot harnessing LLM’s reasoning ability CRISPR-GPT supports four major gene-editing modalities and 22 gene-editing experiment tasks…
GGenetics
Predicting resistance to chemotherapy using chromosomal instability signatures
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Predicting resistance to chemotherapy using chromosomal instability signatures

  • August 2, 2025
CIN signatures as biomarkers of chemotherapy resistance The presence of CIN in a tumor has long been recognized…
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