The heart effects of antidepressants may depend as much on the patient as the drug
A major analysis of randomized trials tracked changes in heart rhythm across 10 antidepressants and examined how age,…
Add-on drug lumateperone boosts sexual function in patients with depression
Patients with major depressive disorder (MDD) and an inadequate response to standard antidepressants who received an add- on…
GLP-1 drugs appear psychiatrically safe, but one finding still raises questions
With millions of patients now taking GLP-1 drugs, researchers examined whether concerns about depression and suicidality are supported…
Probiotics for mental health? A new review finds promising signals and major gaps
Researchers map the probiotic strains and gut-brain pathways being investigated across anxiety, depression, bipolar disorder, and schizophrenia, revealing…
Depression shapes how children pay attention to emotional faces
A smile. A frown. The faces a child pays closer attention to might offer invaluable insight into their…
Ghrelin rises in depression despite obesity’s usual appetite-hormone suppression
A new study finds elevated active and deacylated ghrelin in unmedicated patients with both major depression and obesity,…
How could bisphenol A raise depression risk? Study identifies six key molecular targets
Researchers combined genetic epidemiology, transcriptomics, molecular docking, and mouse experiments to show how a common endocrine-disrupting chemical may…
NOX-1 identified as key molecular target to prolong ketamine’s antidepressant effects
Treatment-resistant depression affects a large proportion of people with major depressive disorder, and while ketamine offers rapid relief,…
New review calls for biologically grounded approach to psychiatric diagnosis
A comprehensive invited review published today in Brain Medicine confronts one of the most persistent paradoxes in modern…
Short-duration psychedelic therapy shows promise for major depression treatment
A controlled clinical trial suggests a fast-acting psychedelic approach may reduce depressive symptoms, but researchers stress careful interpretation…
Research reveals dual impact of brain stimulation on people with depression and anxiety
Research investigating the effects of transcranial direct current stimulation (tDCS) on individuals with depression and comorbid anxiety reveals…
Improving survival in people with severe psychiatric disorders
An expert editorial suggests that widely used diabetes and obesity drugs may help close the long-standing mortality gap…