AI uncovers how DNA architecture failures trigger blood cancer
Cancer isn’t just about broken genes-it’s about broken architecture. Imagine a city where roads suddenly vanish, cutting off…
Bacterial enzyme linked to heart complications in pneumonia
Pneumonia is a disease that burdens the healthcare system with more that 1.2 million emergency room visits each…
AI model popEVE: Prioritizing genetic variants effectively
By combining deep evolutionary signals with human population data, the popEVE model provides a novel approach to identifying…
Genetic signals reveal why erectile dysfunction develops and who is most at risk
New genomic evidence unmasks the biological pathways driving erectile dysfunction, linking cardiometabolic disease and addiction traits to ED…
Discovery of sequence-driven DNA methylation offers new path for epigenetic engineering
All the cells in an organism have the exact same genetic sequence. What differs across cell types is…
Subtle changes in the composition of short tandem repeats may shape disease risk
Scientists at The Hospital for Sick Children (SickKids) have revealed a previously overlooked layer of genetic variation that…
Study clarifies how biliary atresia overlaps with multiple congenital syndromes
Biliary atresia (BA) represents one of the leading causes of pediatric liver failure, often requiring surgical intervention or…
Exploring endogenous retroviruses as hidden drivers of alcohol use disorder
Alcohol use disorder (AUD), characterized by uncontrollable alcohol consumption due to physical and psychological dependence, affects approximately 14.1…
Redefining control in anaerobic microbiome workflows
In this interview, Sheela Muley, Product Manager at Molecular Devices, and Dr Sushmita Sudarshan, Application Scientist in Assay Development at Molecular Devices,…
Study finds high intake of ultra-processed foods tied to reduced DNA methylation
Researchers have found that women who consume more ultra-processed foods exhibit widespread differences in DNA methylation, suggesting early…
Global study suggests potential for universal vaccine against Haemophilus influenzae
A vaccine that tackles the bacteria that cause up to 200 million childhood infections every year could be…
Novel 3D chromosome mapping method can reliably reveal hidden structural variants
Standard laboratory tests can fail to detect many disease-causing DNA changes. Now, a novel 3D chromosome mapping method…