Memory B cells reveal how nasal vaccines could stop respiratory infections earlier
New insights into lung-resident memory B cells show why the next generation of vaccines may need to protect…
BCG vaccine may remodel the human brain’s immune environment
New research led by Mass General Brigham investigators suggests that the Bacillus Calmette-Guérin (BCG) vaccine – which is…
Engineered scaffold restores skull growth in craniosynostosis mouse models
An engineered triphasic biomaterial scaffold successfully recreated the cranial suture stem cell niche lost in craniosynostosis, a condition…
New breast cancer classification system predicts immunotherapy response success
The advent of immune checkpoint inhibitors (ICIs) has marked a paradigm shift in cancer treatment, yet a significant…
COVID-19 vaccine boosters may protect against future animal coronavirus outbreaks
COVID-19 vaccine boosters not only protect against SARS‑CoV‑2 – the virus behind the most recent pandemic – but…
Probiotic metabolite found to suppress melanoma tumor growth in mice
Immune checkpoint inhibitors like anti-PD-1 have transformed melanoma treatment, yet more than half of patients fail to respond…
Nasal viruses may drive allergic rhinitis, and ribavirin shows early promise as a targeted spray treatment
A new study suggests that clearing symptom-driving nasal viruses could calm allergic inflammation and open a fresh treatment…
Study highlights variable synbiotic relationship of prebiotics and probiotics
Adults with obesity who consumed a dietary fiber supplement had positive effects on high-density lipoprotein cholesterol (HDL-C) and…
Modified injectable vaccine shows promise for complete polio eradication
In the United States, children routinely receive an injectable form of the polio vaccine. This vaccine is very…
New review highlights how glutamine metabolism shapes the complex tumor microenvironment
A new review article highlights the expanding importance of glutamine metabolism in shaping the tumor microenvironment, offering fresh…
What medicine-exposed rats reveal about the next urban zoonotic threat
A new study reveals that urban rats are absorbing human medicines from polluted environments, and these hidden pharmaceutical…
Turning the flu virus Into a powerful tool to fight cancer
A recent Views & Comments article published in Engineering highlights advances in repurposing influenza viruses as flexible therapeutic…