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Browsing Tag

neurodegeneration

37 posts
HHealth
Brain organoid studies on the ISS move closer to new treatments
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Brain organoid studies on the ISS move closer to new treatments

  • August 20, 2026
Research using human brain organoids onboard the International Space Station International Space Station (ISS) helped lead to the…
HHealth
Unraveling adult ADHD symptoms through genetics and data science
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Disrupted RNA methylation pathway accelerates Alzheimer’s and Parkinson’s risks

  • August 7, 2026
A growing understanding of RNA biology is reshaping how scientists view the relationship between environmental toxicants, brain development,…
HHealth
Study: AI-redesigned starting points and outcomes enhance protein evolution. Image Credit: Corona Borealis Studio / Shutterstock
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AI redesign helps enzymes evolve beyond natural limits

  • July 24, 2026
By stabilizing enzyme starting points before evolution, researchers opened new mutational routes for engineering highly specific proteases, including…
HHealth
Frequent TV watching links to higher white matter lesion volume
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Frequent TV watching links to higher white matter lesion volume

  • July 23, 2026
A 24-year ARIC analysis suggests that the setting in which people sit may matter for brain measures linked…
HHealth
Brighter Side of News
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Scientists discover new cause of neuron death in Alzheimer’s and dementia

  • June 27, 2026
Cell death in dementia has long posed a frustrating problem. Toxic proteins pile up inside neurons in Alzheimer’s…
HHealth
Study: Western diet induces iron-dependent enteric neurodegeneration via ferroptosis. Image Credit: Yuriy Golub / Shutterstock
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Western diet weakens the gut’s nervous system through iron-dependent damage

  • June 11, 2026
A new study suggests that saturated fat exposure may damage the gut’s own nervous system by triggering iron-dependent…
HHealth
Weight regain observed in patients after ending obesity drug treatment
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Obesity and Alzheimer’s linked through early metabolic disruptions

  • May 6, 2026
By 2030, the population in the United States aged 65 and older is expected to reach 71 million…
HHealth
Uncovering the secrets of ‘SuperAgers’ and cognitive longevity
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Study links antimicrobial peptides to amyloid disease and neurodegeneration

  • May 5, 2026
Background For decades, antimicrobial peptides (AMPs) and amyloid-forming peptides were studied in largely separate contexts. AMPs were viewed…
HHealth
Blood sample tube with Alzheimer test label on medical laboratory technologist hands over blue background
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Identifying the ages when Alzheimer’s biomarkers sharply change

  • May 2, 2026
New research pinpoints the ages when Alzheimer’s-related brain changes accelerate, offering critical clues to when screening may be…
HHealth
Study: Brain Health Across the Life Span: A Framework for Future Studies: A Scientific Statement From the American Heart Association. Image Credit: Anton Vierietin / Shutterstock
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AHA calls for lifelong brain health strategy to prevent cognitive decline

  • April 30, 2026
From childhood stress and pollution to sleep, inflammation, and the gut microbiome, the AHA’s new framework shows why…
HHealth
Innate immune activation and microglial transition during neurodegeneration. (A) During neurodegeneration, distressed neurons release DAMPs such as mtDNA, ROS, HMGB1, aberrant proteins, and pTau–bound RNA. These signals activate resident microglia and astrocytes, which then recruit peripheral immune cells. As shown in more detail in B, activated microglia upregulate PRRs, including TLRs, RAGE, and cGAS, enabling detection of neuron-derived DAMPs. Engagement of PRRs induces proinflammatory gene expression programs and activates inflammasome pathways that promote release of chemokines and cytokines into the CNS parenchyma. As microglia transition from homeostatic to reactive states in a TREM2-dependent manner, damage-associated microglia increase MHC-II expression to support antigen presentation and coordination of adaptive immune responses that attempt to limit neurodegeneration.
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How the immune system may influence Alzheimer’s, Parkinson’s, and related diseases

  • April 17, 2026
A sweeping review shows how the brain’s immune defenses can both fight and fuel neurodegeneration, revealing why timing,…
HHealth
Insights into the clinical presentation and management of sellar chondrosarcomas
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Aston University bioscientist receives £125,000 to investigate genetic reasons for neurodegeneration

  • April 15, 2026
Aston University bioscientist Dr John Reynolds has won a £125,000 Springboard grant from the Academy of Medical Sciences…
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