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Browsing Tag

Neurodegenerative Diseases

25 posts
HHealth
Study reveals how aging reshapes protein chemistry in the brain
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Imaging technique uncovers how copper imbalance may contribute to neurodegenerative diseases

  • July 13, 2026
Using a groundbreaking imaging technique, a University of Houston chemist is uncovering how copper imbalances in the body…
HHealth
Study Reveals How Excess Iron in Neurons Weakens Brain Defences Against Stressors, ETHealthworld
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Study Reveals How Excess Iron in Neurons Weakens Brain Defences Against Stressors, ETHealthworld

  • June 27, 2026
New Delhi: Researchers have found that excess iron in neurons could lower the brain cells’ defences, increasing vulnerability…
NNutrition
Keto Diet May Help Protect Against Multiple Brain Diseases, Study Finds
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Keto Diet May Help Protect Against Multiple Brain Diseases, Study Finds

  • June 3, 2026
A diet designed for weight loss could offer a different bonus benefit, according to a new review. Researchers…
HHealth
Innate immune activation and microglial transition during neurodegeneration. (A) During neurodegeneration, distressed neurons release DAMPs such as mtDNA, ROS, HMGB1, aberrant proteins, and pTau–bound RNA. These signals activate resident microglia and astrocytes, which then recruit peripheral immune cells. As shown in more detail in B, activated microglia upregulate PRRs, including TLRs, RAGE, and cGAS, enabling detection of neuron-derived DAMPs. Engagement of PRRs induces proinflammatory gene expression programs and activates inflammasome pathways that promote release of chemokines and cytokines into the CNS parenchyma. As microglia transition from homeostatic to reactive states in a TREM2-dependent manner, damage-associated microglia increase MHC-II expression to support antigen presentation and coordination of adaptive immune responses that attempt to limit neurodegeneration.
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How the immune system may influence Alzheimer’s, Parkinson’s, and related diseases

  • April 17, 2026
A sweeping review shows how the brain’s immune defenses can both fight and fuel neurodegeneration, revealing why timing,…
HHealth
AlphaFold3 predicts bitter taste receptor structures with greater accuracy
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Gladstone investigator wins MIND Prize to decode hidden Alzheimer’s genetics

  • April 7, 2026
Gladstone Institutes investigator Ryan Corces, PhD, has been named a 2026 winner of the Pershing Square Foundation’s MIND Prize, a…
HHealth
Brighter Side of News
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New AI blood test can help detect several brain diseases at once

  • April 4, 2026
Memory loss can point in more than one direction. A patient may seem to fit Alzheimer’s disease, only…
HHealth
Middle precentral gyrus plays key role in orchestrating speech movements
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New study identifies specific brain cells most vulnerable to ALS and dementia

  • March 12, 2026
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) belong to a spectrum of neurodegenerative diseases with overlapping symptoms,…
HHealth
Study reveals how aging alters liver function and structure
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Scientists map epigenetic changes across aging brain cells

  • March 11, 2026
Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer’s to Parkinson’s…
HHealth
Middle precentral gyrus plays key role in orchestrating speech movements
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Grant supports research into how microglia may spread toxic tau in Alzheimer’s

  • February 21, 2026
A researcher with the Glenn Biggs Institute for Alzheimer’s and Neurodegenerative Diseases at UT Health San Antonio has…
HHealth
Senior women are doing exercise with hoop for fitness and coordination
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Regular aerobic exercise slows a key marker of brain aging in midlife

  • January 22, 2026
A year of consistent aerobic activity didn’t just boost fitness; it shifted MRI-based brain age in early to…
SScience
Uncovering the secrets of ‘SuperAgers’ and cognitive longevity
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MIT researchers map dynamic fuzzy coat surrounding tau protein fibrils

  • January 15, 2026
One of the hallmarks of Alzheimer’s disease is the clumping of proteins called Tau, which form tangled fibrils…
SScience
New insights reveal persistent genome structure during cell division
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Opposing protein forces fine tune mRNA stability in human cells

  • December 17, 2025
A newly revealed molecular tug-of-war may have implications for better understanding how a multitude of diseases and disorders…
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