Safety and security of large language models in healthcare
Gommers, J. et al. Interval cancer, sensitivity, and specificity comparing AI-supported mammography screening with standard double reading without…
Health system learning enables generalist neuroimaging models
Health system learning We define ‘health system learning’ as learning directly from uncurated data generated during routine clinical…
Generative AI-enabled clinical decision support system in primary care: a pragmatic, cluster-randomized trial
Design We conducted a pragmatic, multicenter, parallel-group cluster-randomized controlled trial across a network of 16 primary care facilities…
Effects of exercise and liraglutide on vascular health and inflammation during weight loss maintenance: a prespecified secondary analysis of the S-LiTE trial
Study design This study is a secondary analysis of a randomized, placebo-controlled trial. The trial is registered with…
Towards autonomous medical artificial intelligence agents
MIMIC-IV datasetDataset description We develop a benchmark of 574 patients derived from the MIMIC-IV database which is a…
Mini Brains Help Identify Treatment for Rare Form Parkinson’s Disease
Credit: wildpixel / iStock / Getty Images Plus Brain organoids created in the lab using patient cells have…
AI framework for multidisease detection via retinal imaging
Study population For the model training, we used CFPs from the UKB and three hospital-based centers in China…
Intermittent Fasting Reduces Crohn’s Disease Activity by 40% in Pilot Study
Credit: SEBASTIAN KAULITZKI/SCIENCE PHOTO LIBRARY/Getty Images A randomized clinical trial led by researchers at the University of Calgary…
Childhood ADHD Tied to Higher Risk of Physical Health Problems by Midlife
Credit: SIphotography/Getty Images People who show attention-deficit/hyperactivity disorder (ADHD) traits in childhood are more likely to experience physical…
An LLM chatbot to facilitate primary-to-specialist care transitions: a randomized controlled trial
Ethics approval The Chinese Academy of Medical Sciences and Peking Union Medical College and the local medical ethics…
Single-cell RNA transcriptomics divulged altered gene expressions in monocytes and HLA variations in decompensated cirrhosis patients with sepsis
Single-cell transcriptomic profiling of PBMCs Clinical and biochemical characteristics of all DLC patients with sepsis (n = 11, age 44…
Reporter’s Notebook: The Overdue Breakout for Gene Therapy and Gene Editing
As gene editing enters a new era, leaders discuss Baby KJ’s implications for families, science, and industry. (Left…