Comprehensive genetic map offers new hope for tuberculosis treatments
Rockefeller scientists have created the most comprehensive map to date of how essential genes interact in Mycobacterium tuberculosis…
New computational tool simulates evolution of jumping genes
A genome contains all of the DNA of every living organism, but its contents don’t stop there –…
DNA typewriter to map mouse embryonic development
Almost half a century ago, biologists at the MRC Laboratory of Molecular Biology in Cambridge mapped the complete…
Novel gene rejuvenation therapy preserves cell identity while reversing age
Every organ and tissue progressively loses function and integrity as it ages. In fact, researchers have identified “hallmarks…
Tiny archaeon offers new clues to the minimum genetic requirements for life
Scientists have discovered a previously unknown microorganism, which has the smallest genome ever found, that is possibly able…
DNA Typewriter tracks cell divisions and developmental decisions in mice
Scientists have succeeded in reconstructing the family tree of cells in a developing mouse embryo. They recorded cells’…
New prime assembly method enables long and precise DNA insertions
Genomic editing holds great potential yet continues to have its limitations. Most current methods either rely on untargeted gene…
Study identifies DNA loops as essential for tissue regeneration
After an injury, DNA not only alters its activity but also the way it is organized spatially within…
Blood protein profiling could improve rare disease diagnosis
Researchers from Queen Mary University of London, the Berlin Institute of Health at Charité (BIH) and Genomics England…
New genetic map helps track aggressive prostate cancer development
Prostate cancer is the second most common form of cancer among men globally. Yet, we still know relatively…
Caloric restriction reduces genetic mutations across the mouse genome
Mutations are changes in the molecular “letters” that make up DNA, the genetic blueprint for cells. Mutations build…
Ancient DNA Rewrites Story of Enigmatic ‘American Cheetah’
For several decades, paleontologists have described Miracinonyx trumani — an extinct species of cheetah-like felid that roamed the…