Earliest Organisms on Earth Built Their Biochemistry around Molybdenum, Study Suggests
New research reveals that 3.4 billion years ago (Archean Eon), ancient microbes relied on molybdenum — a metal…
Study links polyploid cancer cells to tumor invasion and spread
One of the biggest challenges in cancer research is understanding why some tumor cells become especially aggressive, invasive…
Study finds no benefit of stronger antibiotics for sinusitis
Acute sinusitis leads to more antibiotic prescriptions for U.S. adults than any other condition, but there is no…
APC-deficient cancer cells rely on single enzyme for survival
A newly published study reports that APC-deficient cancer cells may depend on a single metabolic enzyme for survival,…
OICR funds four Ontario teams to develop next-generation cancer therapies
Better cancer care depends on better treatment options. That’s why the Ontario Institute for Cancer Research (OICR) is…
Metabolic Enzyme Identified as a Selective Vulnerability in APC-Deficient Cancer Cells
Validation of ALDH2 as a synthetic lethal partner of APC using xenograft tumor models Synthetic lethality in APC-deficient…
CiQUS researchers develop flexible chemical strategy to create biomimetic synthetic cells
A team at the Center for Research in Biological Chemistry and Molecular Materials (CiQUS) at the University of Santiago de…
Blocking nitric oxide suppresses tumor growth in aggressive pediatric neuroblastoma
The tumor begins before birth. Somewhere in the developing fetus, neural crest cells that should have matured into…
Challenging processed meat risks for dry-cured ham consumption
New evidence challenges assumptions about processed meats, suggesting that not all cured products carry the same cardiometabolic risks…
New strategy exploits specific genetic vulnerability in colorectal cancer patients
Researchers have identified a novel therapeutic approach for colorectal cancer by exploiting a specific genetic vulnerability found in…
Metabolic pathways drive progression from pancreatic lesions to cancer
Pancreatic ductal adenocarcinoma is the most common type of pancreatic cancer and has a low five-year survival rate.…
New drying technique stabilizes vital vaccines at room temperature
A significant challenge in global healthcare and biotechnology is the “cold chain”-the network of refrigerated storage and transport…