Stem Cell Aging: Why Tissue Repair Slows With Age
IntroductionWhat is stem cell exhaustion?The connection between stem cell exhaustion and other hallmarks of agingHow do inflammation and…
Clinical Trial Shows Positive Results of Enhanced CAR T-Cell Therapy for Patients with B-Cell Blood Cancers
Newswise — Results from a phase I clinical trial led by The Ohio State University Comprehensive Cancer Center…
New BCR analysis method tracks immune recovery after stem cell transplantation
A research team led by Associate Professor Yohei Funakoshi, Associate Professor Kimikazu Yakushijin, and Professor Hironobu Minami of…
AI Can Detect Hidden Signs of Aging in the 3D Architecture of DNA
A new AI tool can read hidden signatures of aging from ordinary microscopy images of blood-forming stem cells.…
Flatworm genes reveal secrets to regrowing damaged brain cells
The human brain is terrible at healing itself from injury or disease. But some animals can harness their…
Study uncovers how interferon-alpha treats rare blood cancers
The biologic drug interferon-alpha can benefit patients with blood cancers called myeloproliferative neoplasms by forcing mutant blood stem…
Brain organoids reveal how Alu-mediated gene deletion can lead to neurodegeneration
Brain diseases, including dementia, have long been studied using experimental animals such as mice. However, differences between the…
Penn State team lays groundwork to 3D print spheroids for regenerating bone tissue
An interdisciplinary team of engineers and chemists at Penn State has laid the groundwork to 3D print spheroids…
New lab-grown heart valves advance treatments for childhood heart diseases
Melbourne researchers have created human heart valve tissues from stem cells, providing a powerful new platform to advance…
New study uncovers metabolic vulnerability in high-risk myelodysplastic syndromes
Researchers at the University of Colorado Anschutz Cancer Center have identified a previously unknown metabolic weakness in the…
Blocking ZFP36L2 protein may disrupt colorectal cancer metastatic growth
Digestion is hard on the cells that line the human gut, and they are constantly being shed and…
Nerve-blocking therapy improves growth plate repair in injured bones
With the support of National Institutes of Health funding, Johns Hopkins Medicine investigators, led by pathologist Aaron W.…