Next-generation sequencing expands possibilities for newborn screening
Every year, millions of newborns undergo routine screening as a preventive strategy to detect inherited disorders before symptoms…
Genetic ancestry influences tumor biology and survival in head and neck cancers
Genetic ancestry plays a key role in determining the behavior of head and neck tumors and may help…
Data-driven modeling uncovers dynamic genome folding in three dimensions
Chromosomes are masters of organization. These long strings of DNA fold down into an ensemble of compact structures…
Genes Tie Gut Motility to Surprising Nutrient: Vitamin B1
Analyzing data from more than 268,000 people, researchers found that genes involved in thiamine (vitamin B1) metabolism play…
Study traces deep origins of syphilis to prehistoric Americas
A newly sequenced genome of the bacterium that causes syphilis, Treponema pallidum, highlights the deep antiquity of treponemal diseases in…
Biologists ‘Resurrect’ 3.2-Billion-Year-Old Enzyme | Sci.News
A team of researchers led by the University of Wisconsin-Madison has reverse-engineered a primordial nitrogen-fixing enzyme, illuminating how…
Large study identifies more than 100 genetic regions linked to schizophrenia
A team of researchers led by scientists from the Icahn School of Medicine at Mount Sinai, SUNY Downstate…
Single-cell technique maps pre-malignant gene mutations in solid tissues
A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the…
Alternative splicing of DOC2A gene shown to drive schizophrenia risk
In an important new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of the…
A safer gene-editing tool shows promise for transthyretin amyloidosis treatment
Genetic disorders occur due to alterations in the primary genetic material, deoxyribonucleic acid (DNA), of an organism. Transthyretin…
14,400-Year-Old Woolly Rhinoceros Genome Shows No Evidence of Recent Inbreeding
The woolly rhinoceros (Coelodonta antiquitatis) is a cold-adapted herbivore that went extinct around 14,000 years ago, but little…
Key protein in the tuberculosis bacterium helps protect itself from foreign DNA
Researchers at the Indian Institute of Science (IISc), with collaborators from the Institute of Mathematical Sciences (IMSc), have…