Understanding leptin’s dual function in MAFLD pathogenesis
Metabolic dysfunction-associated fatty liver disease (MAFLD) has emerged as a predominant chronic liver condition globally, intricately linked with…
Switching APOE4 to APOE2 in adult mice reduces Alzheimer’s pathology and improves memory
By flipping a single genetic switch from APOE4 to APOE2 in adult mice, researchers reversed key Alzheimer’s-like changes…
Study clarifies how biliary atresia overlaps with multiple congenital syndromes
Biliary atresia (BA) represents one of the leading causes of pediatric liver failure, often requiring surgical intervention or…
One-time CRISPR therapy safely lowers cholesterol and triglycerides in early trial
In a 15-patient, Phase 1 one, first-in-human trial, a one-time, CRISPR-Cas9 gene-editing therapy safely reduced LDL cholesterol and…
Low-dose THC mitigates harmful side effects and inflammation caused by HIV treatment
Long-term, low doses of THC mitigate many harmful side effects and inflammation caused by HIV and antiretroviral therapy…
Inconsistent labels and risky doses found in turmeric supplements worldwide
An new study reveals major gaps in the regulation and transparency of turmeric supplements, highlighting how weak oversight…
Early elevation of complement-related proteins in metabolic dysfunction-associated steatotic liver disease (MASLD) with normal liver enzymes | BMC Gastroenterology
Riazi K, Azhari H, Charette JH, Underwood FE, King JA, Afshar EE, et al. The prevalence and incidence…
TRF1 protein depletion linked to leaner mice and altered metabolism
A new research paper was published in Volume 17, Issue 9 of Aging-US on September 17, 2025, titled “Depletion of the…
Pigments extracted from the henna dye could be used to treat liver disease
Lawsonia inermis is best known for making henna, a versatile dye that is used to change the color…
Lilly invests in epigenetic reprogramming biotech
NewLimit adds $45m in new funding at a $1.6bn valuation following preclinical progress that brings clinical trials closer…
Groundbreaking 3D dynamic cell co-culture models simulate MASLD progression
In a recent work published in BME Frontiers, a collaborative study by researchers from Griffith University, Queensland University…
Scientists question the safety and efficacy of the diet for metabolic health
A study published in Science Advances by University of Utah Health researchers sheds light on the long-term effects…