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Browsing Tag

Neurodegenerative Diseases

33 posts
HHealth
Spiritual care should be routine for patients with neurological diseases
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Shared protein pathology redefines treatment for multiple neurodegenerative diseases

  • August 24, 2026
On the surface, amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and limbic-predominant age-related TDP-43 encephalopathy (LATE) might seem…
HHealth
Study links poor sleep to adverse health outcomes in seniors
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Nocturnal micro-awakenings linked to genetic risk of Alzheimer’s disease

  • August 11, 2026
What if certain signs of the disease were to manifest themselves subtly during sleep, long before the first…
HHealth
SLIT2 protein levels in the eye and blood linked to cognitive function
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Sleeping longer may signal early Alzheimer’s-related brain changes

  • July 16, 2026
Regularly sleeping long hours each night is associated with higher levels of an Alzheimer’s-related protein in the blood,…
HHealth
SLIT2 protein levels in the eye and blood linked to cognitive function
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Imaging technique uncovers how copper imbalance may contribute to neurodegenerative diseases

  • July 13, 2026
Using a groundbreaking imaging technique, a University of Houston chemist is uncovering how copper imbalances in the body…
HHealth
NIH Study: Blood Test Using Circular RNAs Predicts Alzheimer’s Progression
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NIH Study: Blood Test Using Circular RNAs Predicts Alzheimer’s Progression

  • July 6, 2026
Elevated levels of specific circular RNAs in the blood nearly tripled the risk of developing Alzheimer’s disease symptoms,…
HHealth
Scientists reveal how cGAS-STING fuels brain inflammation and neurodegeneration
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Scientists reveal how cGAS-STING fuels brain inflammation and neurodegeneration

  • June 11, 2026
A major immune pathway once known for detecting DNA damage is now being linked to brain aging, glial…
NNutrition
Keto Diet May Help Protect Against Multiple Brain Diseases, Study Finds
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Keto Diet May Help Protect Against Multiple Brain Diseases, Study Finds

  • June 4, 2026
A diet designed for weight loss could offer a different bonus benefit, according to a new review. Researchers…
HHealth
Blood-based biomarkers reveal barriers to diversity in Alzheimer’s disease trials
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Virtual reality navigation deficits predict future brain volume loss

  • May 27, 2026
Alzheimer’s disease (AD) often begins long before it is clinically recognized, with subtle brain changes emerging years before…
TTechnology
Novel RNA target offers hope for improving outcomes in patients with chronic limb ischemia
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L-arginine stabilizes protein droplets and prevents harmful fibril formation

  • April 24, 2026
Protein droplets serve important biological functions within cells, but in neurodegenerative diseases like Alzheimer’s, these liquid-like droplets can…
HHealth
Brain circuit identified as key to repetitive and compulsive behaviors in mice
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Microglia actively shape glioblastoma growth and tumor spread

  • April 22, 2026
Glioblastoma, the most common and most aggressive brain tumor type in adults, remains difficult to treat because it…
HHealth
Proteomics analytical pipeline in precision medicine. Review: The emerging role of high-throughput proteomics in advancing precision medicine
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Proteomics and AI bring earlier risk prediction into sharper focus

  • April 20, 2026
From Alzheimer’s risk to cardiovascular prediction, this review shows how protein profiling and AI could help detect disease…
HHealth
Innate immune activation and microglial transition during neurodegeneration. (A) During neurodegeneration, distressed neurons release DAMPs such as mtDNA, ROS, HMGB1, aberrant proteins, and pTau–bound RNA. These signals activate resident microglia and astrocytes, which then recruit peripheral immune cells. As shown in more detail in B, activated microglia upregulate PRRs, including TLRs, RAGE, and cGAS, enabling detection of neuron-derived DAMPs. Engagement of PRRs induces proinflammatory gene expression programs and activates inflammasome pathways that promote release of chemokines and cytokines into the CNS parenchyma. As microglia transition from homeostatic to reactive states in a TREM2-dependent manner, damage-associated microglia increase MHC-II expression to support antigen presentation and coordination of adaptive immune responses that attempt to limit neurodegeneration.
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How the immune system may influence Alzheimer’s, Parkinson’s, and related diseases

  • April 17, 2026
A sweeping review shows how the brain’s immune defenses can both fight and fuel neurodegeneration, revealing why timing,…
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