SGLT2 inhibitors show consistent cardio-renal protection in 70,000 patients
In late-breaking presentations at the American Society of Nephrology Kidney Week meeting and simultaneously published in two companion…
Mismatch in kidney tests may reveal hidden health risks
A mismatch between two common tests for kidney function may indicate a higher risk for kidney failure, heart…
Multiple protein forms from a single gene offer fresh insight into rare disease mechanisms
Iain Cheeseman and colleagues reveal the underappreciated role of single genes producing multiple proteins in atypical presentations of…
Comprehensive kinase atlas reveals new insights into cell signaling and disease
The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme’s…
Study identifies molecular brake that controls overactive killer T cells
“Why do immune cells that are supposed to eliminate viruses suddenly turn against our own body?” There are…
How walnuts combat inflammation and oxidative stress in the body
From protecting brain cells to modulating immunity, walnut bioactives demonstrate remarkable antioxidant and anti-inflammatory potential; however, scientists caution…
Northwestern team develops antibody to expose hidden pancreatic cancer cells
Pancreatic cancer is notoriously hard to treat and often resists the most advanced immunotherapies. Northwestern Medicine scientists have…
Researchers identify new molecular switch involved in programmed cell death
In the fight against disease, programmed cell death – also known as apoptosis – is a key protective…
Scientists uncover new obesity genes that reshape understanding of weight and disease risk
A global research team maps how rare and common gene variants jointly drive obesity and metabolic disease, offering…
Everything is protein, but protein isn’t everything. Here’s what to know
Why do we need protein? Protein is necessary for human life. Fat and carbohydrates are our primary fuel,…
How meals this weekend can impact your daylight saving recovery
As Americans prepare to turn their clocks back this weekend, experts say your diet may determine how sluggish or energized…
Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers
Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and…