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Browsing Tag

Receptor

128 posts
MMedication
Close-up of woman holding GLP-1 injection pen near stomach, modern medical treatment for weight loss and blood sugar control
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People judge GLP-1 users more harshly than dieters

  • May 8, 2026
Even as GLP-1 medications transform obesity treatment, new research reveals a surprising reality: people may face stigma whether…
HHealth
Study: Postprandial lipid metabolism durably enhances T cell immunity. Image Credit: Vink Fan / Shutterstock
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Food timing may shape how T cells respond to infection and therapy

  • May 1, 2026
A new study reveals how lipids released after a meal can durably boost T cell metabolism, translation, and…
TTechnology
Experts call for action against imposter participants in health studies
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Single-cell sequencing reveals why some CAR-T therapies succeed while others fail

  • April 30, 2026
By mapping CAR-T cells one by one, researchers are uncovering the cellular traits that may separate durable cancer…
HHealth
Review: Seven decades after the Asian influenza pandemic: A historical review about immunity and vaccines against H2N2. Image Credit: pedrosek / Shutterstock
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Why H2N2 flu is back on the pandemic preparedness radar

  • April 29, 2026
Decades after H2N2 vanished from humans, declining immunity and persistent animal reservoirs are renewing calls for stockpile-ready vaccines…
HHealth
Understanding leptin's dual function in MAFLD pathogenesis
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Biliary epithelial cells found to actively prevent liver fibrosis development

  • April 28, 2026
Many liver diseases share a common characteristic: fibrosis, that is, the progressive accumulation of scarring in the liver…
MMedication
Study: Anti-obesity medication use sparks effort-based sanctions and social penalties. Image Credit: Love Employee / Shutterstock
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People judge weight loss more harshly when GLP-1 drugs are involved, study finds

  • April 24, 2026
Even when medication is paired with diet and exercise, people may still feel their weight loss is less…
HHealth
Kenyan bat coronavirus uses human CEACAM6 to enter cells, raising spillover concerns
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Kenyan bat coronavirus uses human CEACAM6 to enter cells, raising spillover concerns

  • April 24, 2026
A newly characterized bat coronavirus can latch onto a human cell receptor found in the lung, giving scientists…
HHealth
Vitamin D2 supplementation linked to decrease in natural vitamin D3 concentration
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Vitamin D may prevent diabetes in people with certain genes

  • April 23, 2026
More than two in five U.S. adults has prediabetes, a condition marked by higher-than-normal blood sugar levels that…
HHealth
Tiny DNA junctions provide feedback to control genetic crossovers
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NHS grant funds study on the use of weight-loss drugs for treating PCOS

  • April 21, 2026
Dr. Shagaf Bakour, a gynecologist and director of medical education at Aston Medical School, has won an NHS…
SScience
Understanding the role of m6A methylation in acute lung injury pathogenesis
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Targeting glutamine metabolism enhances CAR-macrophage cancer therapy

  • April 21, 2026
Tumor-associated macrophages (TAMs) within the tumor microenvironment (TME) exhibit significant metabolic dysregulation, which impairs their antitumor function. Specifically,…
SScience
First FDA-approved islet transplant at UI Health ends insulin dependence
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Researchers discover how cell membrane composition drives cancer proliferation

  • April 17, 2026
Cells are enveloped by a lipid membrane that gives them structure and provides a barrier between the cell…
HHealth
Innate immune activation and microglial transition during neurodegeneration. (A) During neurodegeneration, distressed neurons release DAMPs such as mtDNA, ROS, HMGB1, aberrant proteins, and pTau–bound RNA. These signals activate resident microglia and astrocytes, which then recruit peripheral immune cells. As shown in more detail in B, activated microglia upregulate PRRs, including TLRs, RAGE, and cGAS, enabling detection of neuron-derived DAMPs. Engagement of PRRs induces proinflammatory gene expression programs and activates inflammasome pathways that promote release of chemokines and cytokines into the CNS parenchyma. As microglia transition from homeostatic to reactive states in a TREM2-dependent manner, damage-associated microglia increase MHC-II expression to support antigen presentation and coordination of adaptive immune responses that attempt to limit neurodegeneration.
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How the immune system may influence Alzheimer’s, Parkinson’s, and related diseases

  • April 17, 2026
A sweeping review shows how the brain’s immune defenses can both fight and fuel neurodegeneration, revealing why timing,…
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