Sex hormones dictate how skin stem cells renew themselves
For a long time, differences between females and males were mainly associated with the reproductive organs. Yet organs…
New signaling pathway enhances blood stem cell transplantation outcomes
Gene therapies are used to treat many different blood disorders. However, blood stem cells often fail to achieve…
Cigarette smoke alters lung stem cells to drive specific cancers
Chronic exposure to cigarette smoke may reprogram different populations of lung stem cells, which maintain and repair lung…
New BCR analysis method tracks immune recovery after stem cell transplantation
A research team led by Associate Professor Yohei Funakoshi, Associate Professor Kimikazu Yakushijin, and Professor Hironobu Minami of…
AI Can Detect Hidden Signs of Aging in the 3D Architecture of DNA
A new AI tool can read hidden signatures of aging from ordinary microscopy images of blood-forming stem cells.…
Human Embryo Models Show Important Biological Differences
For decades, scientists have dreamed of peering into the earliest days of human life, those fragile moments when…
Active form of meprin-β protein increases in people with Alzheimer’s disease
A team from the Altered Molecular Mechanism in Alzheimer’s Disease and Dementia laboratory, led by Javier Sáez Valero,…
Study uncovers how interferon-alpha treats rare blood cancers
The biologic drug interferon-alpha can benefit patients with blood cancers called myeloproliferative neoplasms by forcing mutant blood stem…
New drug forces aggressive leukemia cells to die from stress
Pushing the accelerator and the brake at the same time is rarely a good idea. But researchers at…
Researchers maintain brain organoids for longer than ever before
An international team of researchers has maintained brain organoids, three-dimensional models of human brain tissue, for longer than…
Low muscle quality, but not muscle mass, in abdominal CT-scans associates with adverse outcomes in AML patients undergoing an allogeneic stem cell transplantation
For many patients with acute myeloid leukemia (AML), allogeneic hematopoietic stem cell transplantation (HSCT) remains the treatment with…
New heart assembloid model mimics complex valve disorders
A multi-disciplinary, multi-institution group of researchers focused their expertise in genetics, mechanics, chemistry and biology on a chip…