Combined CDK4/6 and EGFR inhibition improves pancreatic cancer therapy
Clinically available KRAS inhibitors mainly target G12C, which is rare in PDAC and often acquires resistance. Oncogenic KRAS…
Higher tyrosine levels linked to shorter lifespan in major UK Biobank analysis
A large genetic analysis suggests that one amino acid linked to protein metabolism could influence how long we…
Comprehensive kinase atlas reveals new insights into cell signaling and disease
The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme’s…
Common food additives may trigger childhood asthma
A recent study published in Frontiers in Immunology utilized metabolomics to investigate the mechanisms underlying the association between food…