Typical research doses range from 800-2000 IU-that’s 20-50 micrograms of vitamin D3, and 90-200 micrograms of vitamin K2-per day, though specific trials vary. More is not always better, say health agencies, since chronic, high-dose vitamin D can cause toxicity, and vitamin K supplements may interact with blood-thinning drugs such as warfarin. Generally, experts recommend testing vitamin D levels and-with a clinician, reviewing medications and medical history before starting combined D3-and K2-supplements rather than taking matters into one’s own hands-with high-dose capsules.
