Age distinguishes selection from causation in cancer genomes
Defining the carcinogenic effect of mutations We defined the carcinogenic effect of a mutation by its influence on…
NHS issues urgent ‘check your skin’ warning for illness that kills thousands
The alert has been issued to mark the beginning of May 2026 amid an attempt to increase awareness…
Genetic association and machine learning improve the prediction of type 1 diabetes risk
Ethics statement The use of human genetic data in this study was approved by the University of California,…
AI framework for multidisease detection via retinal imaging
Study population For the model training, we used CFPs from the UKB and three hospital-based centers in China…
Who owns my health data?
In Europe, nations are feeling pressure to keep the continent competitive in AI while staying inside strict privacy…
Wearables as personal health custodians
UK Department of Health and Social Care. Fit for the Future: 10 Year Health Plan for England (2025).…
Multi-ancestry genome-wide association study of severe pregnancy nausea and vomiting
Fejzo, M. S. et al. Nausea and vomiting of pregnancy and hyperemesis gravidarum. Nat. Rev. Dis. Primers 5,…
De novo formation of cis-regulatory contacts in the absence of NIPBL-driven chromatin loop extrusion
Vermunt, M. W., Zhang, D. & Blobel, G. A. The interdependence of gene-regulatory elements and the 3D genome.…
I’m a cancer specialist – here are six dangerous health myths you should ignore
From when to see a GP to who screening is really for, Professor David Bloomfield, consultant clinical oncologist…
Implementing whole genome and transcriptome sequencing for cancer patients in routine healthcare: a comprehensive guide to costing
Kazdal D, Endris V, Allgauer M, Kriegsmann M, Leichsenring J, Volckmar AL, et al. Spatial and temporal heterogeneity…
Large-scale exome analyses reveal new rare variant contributions in amyotrophic lateral sclerosis
Building a harmonized ALS exome dataset for rare variant analysis To identify rare coding variants involved in ALS,…
Biallelic variants in RNU2-2 cause the most prevalent known recessive neurodevelopmental disorder
Genetic association analysis We identified the recessive form of RNU2-2 syndrome through a joint statistical analysis of the…