Gut microbiome maturation in early childhood interacts with host genetics to predict type 1 diabetes risk
Ethics statement The TEDDY study obtained written informed consent for all study participants from a parent or primary…
Possible relationship between genetic polymorphisms and the risk of exercise addiction among Turkish elite athletes: an exploratory pilot study
The present exploratory pilot study investigated genetic variants potentially associated with EA among elite Turkish athletes using a…
Unpredictability is a childhood adversity that contributes to mental health problems
Felitti, V. J. et al. Relationship of childhood abuse and household dysfunction to many of the leading causes…
A Bayesian framework for longitudinal EHR and genetic discovery
Model We recapitulated the formulation of the model and provide a full account of model assumptions and implementation…
Strengthening the metabolic alliance: exercise as an essential partner of obesity pharmacotherapy
Competing interests J.B. has received speaking fees from Novo Nordisk and Eli Lilly for educational activities related to…
Disparate privacy risks from medical AI
Medical artificial intelligence (AI) has immense potential to improve health outcomes, particularly in regions in which specialized medical…
Effects of exercise and liraglutide on vascular health and inflammation during weight loss maintenance: a prespecified secondary analysis of the S-LiTE trial
Study design This study is a secondary analysis of a randomized, placebo-controlled trial. The trial is registered with…
An AI-based symptom checker integrated into MomConnect maternal healthcare platform: a prospective, observational mixed-methods study
Study design and setting This prospective, observational mixed-methods study validates the integration of a DDSS within a government…
Adiposity and cancer: epidemiology, mechanisms and future perspectives
NCD Risk Factor Collaboration (NCD-RisC). Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis…
Mutation-dependent responses to sleep and exercise in clonal haematopoiesis
Jaiswal, S. & Ebert, B. L. Clonal hematopoiesis in human aging and disease. Science 366, eaan4673 (2019). Article …
The linkage between microbial community dynamics and urbanization age
World Cities Report 2022: Envisaging the Future of Cities (UN-Habitat, 2022). Grimm, N. B. et al. Global change…
Tumour promotion through the lens of evolution
Nowell, P. C. The clonal evolution of tumor cell populations. Science 194, 23–28 (1976). Article CAS PubMed ADS …