A young dad’s colon cancer spread to his lungs with no warning. He says a clinical trial led to a miracle.
Spencer Laird first noticed blood in his stool when he was 25. His doctor thought it was hemorrhoids…
A repeat expansion in GOLGA8A is a major risk factor for atypical frontotemporal lobar degeneration with ubiquitin-positive inclusions
FTLD-FET consortium We established an international consortium to identify and bring together a sufficiently large case population to…
A clinical environment simulator for dynamic AI evaluation
Goh, E. et al. Large language model influence on diagnostic reasoning: a randomized clinical trial. JAMA Netw. Open…
A daily multivitamin slows the ticking of epigenetic clocks – Nature
A daily multivitamin slows the ticking of epigenetic clocks NatureEffects of daily multivitamin–multimineral and cocoa extract supplementation on epigenetic…
Early cancer treatments could accelerate aging in survivors, study finds
NEWYou can now listen to Fox News articles! Surviving cancer as a child or young adult may have…
Vegetarian diets and cancer risk: pooled analysis of 1.8 million women and men in nine prospective studies on three continents
Study population The study design and data harmonisation process have been described in detail elsewhere [17]. Briefly, prospective…
Genome-wide association analyses highlight the role of the intestinal molecular environment in human gut microbiota variation
Ethical considerations The current study has been approved by the Swedish Ethical Review Authority (DNR 2022-06137-01, DNR 2024-01992-02).…
Reliability of LLMs as medical assistants for the general public: a randomized preregistered study
The study employed a between-subjects design with three treatment groups and a control. Before the treatment phase, participants…
Scaling medical AI across clinical contexts
Jiang, L. Y. et al. Health system-scale language models are all-purpose prediction engines. Nature 619, 357–362 (2023). Article …
Mutational scanning reveals oncogenic CTNNB1 mutations have diverse effects on signaling
CTNNB1 hotspot mutational patterns are tissue-specific We analyzed 9,248 tumors with CTNNB1 mutations in the COSMIC database (Fig.…
ER remodelling is a feature of ageing and depends on ER-phagy
In vivo imaging of ER dynamics in adult C. elegans Many ER proteins are enriched in specific structural…
Fecal microbiota transplantation plus immunotherapy in non-small cell lung cancer and melanoma: the phase 2 FMT-LUMINate trial
Study participants and clinical trial design The FMT-LUMINate trial (NCT04951583) is a multicenter, open-label, phase 2 trial that…