Systemic epigenetic dysregulation as a driver of ageing and a therapeutic target
Guo, J. et al. Aging and aging-related diseases: from molecular mechanisms to interventions and treatments. Signal. Transduct. Target.…
Single-cell spatial transcriptomic analysis of human skin anatomy
A single-cell spatial MERFISH atlas of normal human skin To map the cellular and spatial diversity of human…
Effects of daily multivitamin–multimineral and cocoa extract supplementation on epigenetic aging clocks in the COSMOS randomized clinical trial
Wu, Z., Zhang, W., Qu, J. & Liu, G. H. Emerging epigenetic insights into aging mechanisms and interventions.…
Family to host 7K fundraiser run in Cary in honor of daughter who died of rare brain cancer :: WRAL.com
Taylor Anne Huston loved to run. After the 7-year-old girl from Cary passed away in 2022 from a…
A young dad’s colon cancer spread to his lungs with no warning. He says a clinical trial led to a miracle.
Spencer Laird first noticed blood in his stool when he was 25. His doctor thought it was hemorrhoids…
A repeat expansion in GOLGA8A is a major risk factor for atypical frontotemporal lobar degeneration with ubiquitin-positive inclusions
FTLD-FET consortium We established an international consortium to identify and bring together a sufficiently large case population to…
A clinical environment simulator for dynamic AI evaluation
Goh, E. et al. Large language model influence on diagnostic reasoning: a randomized clinical trial. JAMA Netw. Open…
A daily multivitamin slows the ticking of epigenetic clocks – Nature
A daily multivitamin slows the ticking of epigenetic clocks NatureEffects of daily multivitamin–multimineral and cocoa extract supplementation on epigenetic…
Early cancer treatments could accelerate aging in survivors, study finds
NEWYou can now listen to Fox News articles! Surviving cancer as a child or young adult may have…
Vegetarian diets and cancer risk: pooled analysis of 1.8 million women and men in nine prospective studies on three continents
Study population The study design and data harmonisation process have been described in detail elsewhere [17]. Briefly, prospective…
Genome-wide association analyses highlight the role of the intestinal molecular environment in human gut microbiota variation
Ethical considerations The current study has been approved by the Swedish Ethical Review Authority (DNR 2022-06137-01, DNR 2024-01992-02).…
Reliability of LLMs as medical assistants for the general public: a randomized preregistered study
The study employed a between-subjects design with three treatment groups and a control. Before the treatment phase, participants…