Precise DNA base editing using AlphaFold3-based contact modelling
Anzalone, A. V., Koblan, L. W. & Liu, D. R. Genome editing with CRISPR-Cas nucleases, base editors, transposases…
NutriMatch: harmonizing food composition databases with large language models for enhanced nutritional prediction
Data collection We utilized data from the 10K Project, a prospective human cohort study involving over 10,000 healthy…
A universal entropic pulling force caused by binding
Entropic force in a diatomic molecule To illustrate the concept of entropic force, we begin with a simple…
Systema: a framework for evaluating genetic perturbation response prediction beyond systematic variation
Nonparametric baselines We design two nonparametric baselines that we refer to as perturbed mean and matching mean. Perturbed…