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Browsing Tag

Oxidative Stress

37 posts
SScience
New EASD guideline combines clinical standards with lived experience
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Metformin protects neurons after brain injury by restoring mitochondrial health

  • April 13, 2026
TBI remains a major cause of death and long-term neurological disability worldwide, yet effective treatments for secondary injury…
SScience
Mixed grilled meat platter. Assorted grilled meat
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Challenging processed meat risks for dry-cured ham consumption

  • April 7, 2026
New evidence challenges assumptions about processed meats, suggesting that not all cured products carry the same cardiometabolic risks…
HHealth
Review: The Prickly Solution to Metabolic Syndrome: A Multitarget View on the Opuntia ficus-indica Fruit Phytocomplex. Image Credit: anna.q / Shutterstock
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Prickly pear may pack a surprising punch against metabolic syndrome

  • April 7, 2026
This new review explores how prickly pear fruit may act on oxidative stress, inflammation, insulin resistance, and lipid…
HHealth
Study: Palmatine ameliorates MASLD in type 2 diabetes by modulating hepatic apoptosis and inflammation. Image Credit: sasirin pamai / Shutterstock
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Palmatine improved fatty liver markers in a preclinical type 2 diabetes study

  • March 24, 2026
A new preclinical study suggests that palmatine may ease diabetes-linked fatty liver disease by targeting inflammation, oxidative stress,…
HHealth
Female hand with jar of tasty peanut butter, spoon and toasts on white background
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Can peanut butter improve mobility after 65?

  • February 27, 2026
A simple spoonful of peanut butter each day improved lower-body muscle power in older adults, but the study’s…
NNutrition
Martha Stewart Living
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5 of the Best Fruits to Eat for Antioxidants, According to Nutritionists

  • February 24, 2026
Eating antioxidant fruits is one of the simplest (and tastiest) ways to reduce your risk of disease. The…
SScience
Brighter Side of News
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Researchers link ultra-endurance running to accelerated red blood cell aging

  • February 21, 2026
After a long trail race, some of your red blood cells may not bend the way they should.…
SScience
Extreme endurance exercise pushes red blood cells toward accelerated aging
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Extreme endurance exercise pushes red blood cells toward accelerated aging

  • February 18, 2026
Extreme endurance running damages red blood cells in ways that may affect their ability to function properly, according…
HHealth
Lifestyle choices and hormonal imbalances can impact men's reproductive health
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Too many antioxidants may negatively affect future offspring

  • February 5, 2026
Antioxidants have been marketed as miracle supplements, touted for preventing chronic diseases and cancers; treating COPD and dementia;…
HHealth
Balancing copper antimicrobials to combat antibiotic resistance
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Study reveals how antibiotic resistant bacteria delay chronic wound healing

  • January 17, 2026
An international team of scientists, led by Nanyang Technological University, Singapore (NTU Singapore), has discovered a new way…
SScience
Study: Acute Impact of Polyphenol-Rich vs. Carbohydrate-Rich Foods and Beverages on Exercise-Induced ROS and FRAP in Healthy Sedentary Female Adults - A Randomized Controlled Trial. Image Credit: Improvisor / Shutterstock
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How specific foods reshape oxidative stress responses during and after high-intensity training

  • December 12, 2025
A new randomized trial reveals how simple food choices before and after fasted HIIT can shift the body’s…
HHealth
Cellular responses to ischemic reperfusion injury in young vs older donor organs. During ischemia, the deprivation of oxygen and nutrients leads to mitochondrial dysfunction and energy loss. In young cells, mitochondrial resilience helps sustain ATP production, ameliorating damage. Old cells, in contrast, experience significant ATP depletion, relying heavily on anaerobic metabolism, which leads to lactate buildup, pH reduction, and cellular stress. Upon reperfusion, the restoration of blood flow triggers oxidative stress as mitochondria generate excessive reactive oxygen species (ROS). Young cells compensate for those events through robust antioxidant systems, maintaining cellular integrity. Conversely, in old cells, impaired antioxidant defenses result in unregulated ROS production, furthermore damaging membranes, organelles, and DNA. Additionally, old cells release pro-inflammatory genes, amplifying local inflammation. Consequences are particularly severe in aged vascular endothelial cells, with ion pump dysfunction (e.g., Na⁺/K⁺ ATPase) causing ionic imbalances and cellular edema. This disruption exacerbates ischemic injury, progressing to irreversible damage. In contrast, young cells effectively resolve edema and inflammation through mechanisms that include macrophage945 mediated clearance of Damage-Associated Molecular Patterns (DAMPs) and anti-inflammatory cytokine release (e.g., IL-10 and TGF-β), allowing recovery and tissue repair. In old cells, persistent ROS generation, unresolved inflammation, and DAMP accumulation lead to irreversible inflammation, organelle collapse, and eventual cell death. Created in BioRender. Kayumov, M. (2025) https://BioRender.com/m23u7ro .
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Scientists outline how organ rejuvenation strategies could solve the donor shortage

  • December 12, 2025
New insights into cellular aging, perfusion technologies, and senescence-targeting treatments show how aging organs could be revived, turning…
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