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Browsing Tag

Biomedicine

12 posts
GGenetics
Weight-loss associated DNA methylation patterns: targetable biomarkers and pathway insights | BMC Research Notes
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Weight-loss associated DNA methylation patterns: targetable biomarkers and pathway insights | BMC Research Notes

  • July 22, 2025
Processed datasets Public datasets were collected and analyzed independently. We utilized DNAm arrays from the Illumina EPIC platform,…
GGenetics
Sequencing validates deep learning models for EHR-based detection of Noonan syndrome in pediatric patients
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Sequencing validates deep learning models for EHR-based detection of Noonan syndrome in pediatric patients

  • July 21, 2025
Cohort characteristics and model risk score distribution The study cohort comprised 92,493 patients enrolled in the DT Biobank…
GGenetics
Viromics approaches for the study of viral diversity and ecology in microbiomes
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Viromics approaches for the study of viral diversity and ecology in microbiomes

  • July 21, 2025
Koonin, E. V., Kuhn, J. H., Dolja, V. V. & Krupovic, M. Megataxonomy and global ecology of the…
GGenetics
Multiplexed assays of variant effect for clinical variant interpretation
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Multiplexed assays of variant effect for clinical variant interpretation

  • July 21, 2025
Chen, E. et al. Rates and classification of variants of uncertain significance in hereditary disease genetic testing. JAMA…
GGenetics
Machine learning reveals complex genetics of fungal resistance in sorghum grain mold
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Machine learning reveals complex genetics of fungal resistance in sorghum grain mold

  • July 19, 2025
Ackerman A, Wenndt A, Boyles R (2021) The sorghum grain mold disease complex: pathogens, host responses, and the…
GGenetics
Therapeutic strategies for fragile X syndrome and implications for other gene-silencing disorders
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Therapeutic strategies for fragile X syndrome and implications for other gene-silencing disorders

  • July 17, 2025
Ng, S. B. et al. Exome sequencing identifies the cause of a Mendelian disorder. Nat. Genet. 42, 30–35…
GGenetics
How to more efficiently study complex treatment interactions | MIT News
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How to more efficiently study complex treatment interactions | MIT News

  • July 16, 2025
MIT researchers have developed a new theoretical framework for studying the mechanisms of treatment interactions. Their approach allows…
GGenetics
Mapping trait-associated cells with spatial transcriptomics
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Mapping trait-associated cells with spatial transcriptomics

  • July 16, 2025
Genome-wide association studies (GWAS) have uncovered numerous genetic variants associated with complex traits. However, a critical gap remains…
AArtificial intelligence
Deep adaptive learning predicts and diagnoses CSVD-related cognitive decline using radiomics from T2-FLAIR: a multi-centre study
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Deep adaptive learning predicts and diagnoses CSVD-related cognitive decline using radiomics from T2-FLAIR: a multi-centre study

  • July 15, 2025
Patient enrolment and baseline characteristics A total of 783 subjects from three cohorts were included (Fig. S1) and…
AArtificial intelligence
Reshaping transplantation with AI, emerging technologies and xenotransplantation
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Reshaping transplantation with AI, emerging technologies and xenotransplantation

  • July 14, 2025
Bozkurt, B. et al. Heart failure epidemiology and outcomes statistics: a report of the Heart Failure Society of…
GGenetics
Implications of monogenic bicuspid aortic valve (BAV) forms among sporadic BAV patients
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Implications of monogenic bicuspid aortic valve (BAV) forms among sporadic BAV patients

  • July 12, 2025
Siu SC, Silversides CK. Bicuspid aortic valve disease. J Am Coll Cardiol. 2010;55:2789–800. PubMed  Google Scholar  Gehlen J,…
HHealth care
A scoping review of the governance of federated learning in healthcare
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A scoping review of the governance of federated learning in healthcare

  • July 11, 2025
As illustrated in Fig. 1, 39 papers were included in the review, which examined the governance of one…
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