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Browsing Tag

CNS cancer

5 posts
NNutrition
Low carbohydrate high fat diet curbs glioblastoma by shifting lipids and limiting cancer stem cell metabolic flexibility
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Low carbohydrate high fat diet curbs glioblastoma by shifting lipids and limiting cancer stem cell metabolic flexibility

  • July 28, 2026
Metabolic rewiring fuels tumorigenicity of cancer stem cells contributing to universal glioblastoma (GBM) recurrence. Invasive glioblastoma stem cells…
HHealth
Dual tumour–myeloid targeting of glioblastoma with GPNMB CAR-T cells
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Dual tumour–myeloid targeting of glioblastoma with GPNMB CAR-T cells

  • July 2, 2026
Cell lines and patient-derived GSC cultures Human GBM samples were obtained from patients who provided written informed consent…
HHealth
Acquired genetic and cell-state changes in IDH-mutant glioma progression
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Acquired genetic and cell-state changes in IDH-mutant glioma progression

  • June 3, 2026
Human glioma samples Frozen glioma tissue specimens with the IDH1 or IDH2 mutation were collected with informed consent…
HHealth
Dominant clones leverage developmental epigenomic states to drive ependymoma
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Dominant clones leverage developmental epigenomic states to drive ependymoma

  • March 26, 2026
In utero electroporation All animal procedures in this study were performed with approval from the St. Jude Institutional…
HHealth
Multidimensional profiling of heterogeneity in supratentorial ependymomas
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Multidimensional profiling of heterogeneity in supratentorial ependymomas

  • March 12, 2026
Experimental model and participant detailsHuman participants All of the deidentified samples used in this study were obtained after…
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