Real-world, digital-first delivery of GLP-1 receptor agonist therapy in women
Study population Between 27 November 2024 and 31 January 2025, adult women (female sex at birth) were recruited…
Possible relationship between genetic polymorphisms and the risk of exercise addiction among Turkish elite athletes: an exploratory pilot study
The present exploratory pilot study investigated genetic variants potentially associated with EA among elite Turkish athletes using a…
Unpredictability is a childhood adversity that contributes to mental health problems
Felitti, V. J. et al. Relationship of childhood abuse and household dysfunction to many of the leading causes…
Still in the dark: effects of sex differences on statin-associated diabetes risk
Cholesterol Treatment Trialists’ CollaborationEffects of statin therapy on diagnoses of new-onset diabetes and worsening glycaemia in large-scale randomised…
A Bayesian framework for longitudinal EHR and genetic discovery
Model We recapitulated the formulation of the model and provide a full account of model assumptions and implementation…
90 percent of U.S. adults have this syndrome — but most have never heard of it
Susan Gilchrist, a preventive cardiologist and epidemiologist, sees patients all the time at the University of North Carolina…
Strengthening the metabolic alliance: exercise as an essential partner of obesity pharmacotherapy
Competing interests J.B. has received speaking fees from Novo Nordisk and Eli Lilly for educational activities related to…
Effects of exercise and liraglutide on vascular health and inflammation during weight loss maintenance: a prespecified secondary analysis of the S-LiTE trial
Study design This study is a secondary analysis of a randomized, placebo-controlled trial. The trial is registered with…
Adiposity and cancer: epidemiology, mechanisms and future perspectives
NCD Risk Factor Collaboration (NCD-RisC). Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis…
Mutation-dependent responses to sleep and exercise in clonal haematopoiesis
Jaiswal, S. & Ebert, B. L. Clonal hematopoiesis in human aging and disease. Science 366, eaan4673 (2019). Article …
Genetic analysis of circulating metabolic traits in 619,372 individuals
Suzuki, K. et al. Genetic drivers of heterogeneity in type 2 diabetes pathophysiology. Nature 627, 347–357 (2024). Article …
Tumour promotion through the lens of evolution
Nowell, P. C. The clonal evolution of tumor cell populations. Science 194, 23–28 (1976). Article CAS PubMed ADS …