Real-world, digital-first delivery of GLP-1 receptor agonist therapy in women
Study population Between 27 November 2024 and 31 January 2025, adult women (female sex at birth) were recruited…
Probing the many benefits of GLP-1 receptor agonists
RESEARCH HIGHLIGHT 05 October 2026 Glucagon-like peptide 1 (GLP-1) receptor agonists are approved for the treatment of type…
Imputation of fluid intelligence scores reduces ascertainment bias and increases power for analyses of common and rare variants
Ethics oversight UK Biobank obtained ethical approval from the NHS North West Centre for Research Ethics Committee (reference…
Single-nucleus atlas of cell-type specific genetic regulation in the human brain
All procedures and research protocols were approved by the Institutional Review Board (IRBs) of Rush University Medical Center…
Human tau pathology is associated with lonely, nontraveling slow waves linked to memory impairment
Rönnlund, M., Nyberg, L., Bäckman, L. & Nilsson, L.-G. Stability, growth, and decline in adult life span development…
Phenomic profiles and disease patterns of 1.9 million participants from Our Future Health
Ethical approval This study involves data from human participants that have participated in the OFH program and the…
A scoping review on the mental health harms of LLM-based chatbots
Weizenbaum, J. ELIZA—a computer program for the study of natural language communication between man and machine. Commun. ACM…
Histological aging signatures for monitoring tissue-specific aging and disease
Data reporting No statistical methods were used to predetermine sample size due to the predetermined sample availability of…
Psilocybin-assisted therapy for treatment-resistant major depressive disorder in a public healthcare setting: a randomized controlled trial
This study of psilocybin assisted-therapy for TRD—to our knowledge, the first RCT in this population to assess feasibility…
Divergent impacts of explainable AI for dermatological diagnosis on clinicians versus lay people
Study design We designed two complementary large-scale experiments to evaluate human−AI collaborative diagnostic performance across expertise levels (Fig.…
Representations of the intrinsic value of information in mouse orbitofrontal cortex
Subjects All experimental and surgical protocols were performed in accordance with the guide of Care and Use of…
Paired mutation calling and spatial transcriptomics identify cellular neighborhoods associated with the neoplastic outcome of mouse colitis
Mice Mice were of C57BL/6 background. The Muc2KO line used was described by Velcich et al.16. Mice containing…