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Browsing Tag

Life Sciences

117 posts
NNutrition
Low carbohydrate high fat diet curbs glioblastoma by shifting lipids and limiting cancer stem cell metabolic flexibility
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Low carbohydrate high fat diet curbs glioblastoma by shifting lipids and limiting cancer stem cell metabolic flexibility

  • July 28, 2026
Metabolic rewiring fuels tumorigenicity of cancer stem cells contributing to universal glioblastoma (GBM) recurrence. Invasive glioblastoma stem cells…
HHealth
Distinct brain regions mediate regulation of food intake in response to GIPR agonism or antagonism
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Distinct brain regions mediate regulation of food intake in response to GIPR agonism or antagonism

  • July 24, 2026
Dual agonism of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptors (GLP-1R and GIPR, respectively), in the…
SScience
Lipids in ovarian cancer ascites impair T cell activation by disrupting TCR dynamics
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Lipids in ovarian cancer ascites impair T cell activation by disrupting TCR dynamics

  • July 24, 2026
Ovarian Cancer Statistics. How Common is Ovarian Cancer. American Cancer Society https://www.cancer.org/cancer/types/ovarian-cancer/about/key-statistics.html (2026). Schepisi, G. et al. Immunotherapy…
SScience
Genetic trade-offs in fertility and longevity explain the maintenance of disease-associated alleles in humans
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Genetic trade-offs in fertility and longevity explain the maintenance of disease-associated alleles in humans

  • July 22, 2026
Welter, D. et al. The NHGRI GWAS Catalog, a curated resource of SNP-trait associations. Nucleic Acids Res. 42,…
HHealth
Plasma proteome profiling identified biomarkers for the differential diagnosis and molecular staging of neurodegenerative dementias
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Plasma proteome profiling identified biomarkers for the differential diagnosis and molecular staging of neurodegenerative dementias

  • July 21, 2026
Ethics statement All procedures involving human participants were conducted in accordance with the 2013 revision of the Declaration…
HHealth
Mapping in-cell protein contact sites reveals hijacking of paraspeckles during influenza A virus infection
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Mapping in-cell protein contact sites reveals hijacking of paraspeckles during influenza A virus infection

  • July 21, 2026
Immortalized cell lines Human A549 (86012804; ECACC) and HEK293T (CRL-3216; ATCC) cells were cultured in DMEM (11960044; Gibco)…
SScience
Rates of passerine body plan evolution in time and space
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Rates of passerine body plan evolution in time and space

  • July 20, 2026
Jablonski, D., Roy, K. & Valentine, J. W. Out of the tropics: evolutionary dynamics of the latitudinal diversity…
HHealth
A data-driven framework reconstructs the molecular continuum of human MASLD progression
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A data-driven framework reconstructs the molecular continuum of human MASLD progression

  • July 15, 2026
Transcriptomics-based disease trajectory analysis captures MASLD progression We first sought to determine whether MASLD progression could be represented…
SScience
The evolution and diversification of Cetacea
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The evolution and diversification of Cetacea

  • July 14, 2026
Thewissen, J. & Bajpai, S. Whale origins as a poster child for macroevolution. BioScience 51, 1037–1049 (2001). Article …
HHealth
Hypoxia rescues complex 1-associated disease caused by proteostatic defects
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Hypoxia rescues complex 1-associated disease caused by proteostatic defects

  • July 9, 2026
Animal use and care Htra2 mutant mice (mnd2; strain no. 004608, background: C57BL/6J) were obtained from The Jackson…
SScience
Self-generated hydrogel ejects bacterial cells for localized biofilm dispersion
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Self-generated hydrogel ejects bacterial cells for localized biofilm dispersion

  • July 8, 2026
Bacterial strains The B. subtilis strains used in this study are listed in Supplementary Table 1. The capBCAE…
SScience
Delayed molecular aging, preservation of energy metabolism and enhanced exercise response in exercise-trained human muscle
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Delayed molecular aging, preservation of energy metabolism and enhanced exercise response in exercise-trained human muscle

  • July 3, 2026
López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M. & Kroemer, G. The hallmarks of aging. Cell 153,…
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