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Browsing Tag

Animal Genetics and Genomics

84 posts
HHealth
Imputation of fluid intelligence scores reduces ascertainment bias and increases power for analyses of common and rare variants
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Imputation of fluid intelligence scores reduces ascertainment bias and increases power for analyses of common and rare variants

  • October 5, 2026
Ethics oversight UK Biobank obtained ethical approval from the NHS North West Centre for Research Ethics Committee (reference…
HHealth
Single-nucleus atlas of cell-type specific genetic regulation in the human brain
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Single-nucleus atlas of cell-type specific genetic regulation in the human brain

  • September 24, 2026
All procedures and research protocols were approved by the Institutional Review Board (IRBs) of Rush University Medical Center…
HHealth
Human tau pathology is associated with lonely, nontraveling slow waves linked to memory impairment
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Human tau pathology is associated with lonely, nontraveling slow waves linked to memory impairment

  • September 12, 2026
Rönnlund, M., Nyberg, L., Bäckman, L. & Nilsson, L.-G. Stability, growth, and decline in adult life span development…
HHealth
Representations of the intrinsic value of information in mouse orbitofrontal cortex
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Representations of the intrinsic value of information in mouse orbitofrontal cortex

  • August 1, 2026
Subjects All experimental and surgical protocols were performed in accordance with the guide of Care and Use of…
HHealth
Paired mutation calling and spatial transcriptomics identify cellular neighborhoods associated with the neoplastic outcome of mouse colitis
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Paired mutation calling and spatial transcriptomics identify cellular neighborhoods associated with the neoplastic outcome of mouse colitis

  • July 30, 2026
Mice Mice were of C57BL/6 background. The Muc2KO line used was described by Velcich et al.16. Mice containing…
HHealthcare
Translating genomic data into healthcare practice with the Singapore National Precision Medicine program
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Translating genomic data into healthcare practice with the Singapore National Precision Medicine program

  • July 29, 2026
Precision Health Research, Singapore (PRECISE), Singapore, Singapore Shih Wee Seow, Clement Qiwen Sin, Denise Xin Yi Chua, Emily Shu Fang Lau, Gloria…
HHealth
SUMOylation enhances DNMT1 function to repress mega-intergenic RNAs and viral mimicry
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SUMOylation enhances DNMT1 function to repress mega-intergenic RNAs and viral mimicry

  • July 22, 2026
Bostick, M. et al. UHRF1 plays a role in maintaining DNA methylation in mammalian cells. Science 317, 1760–1764…
HHealth
Genome-wide association analyses of borderline personality disorder identify 11 loci and highlight shared risk with mental and somatic disorders
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Genome-wide association analyses of borderline personality disorder identify 11 loci and highlight shared risk with mental and somatic disorders

  • July 21, 2026
Hector Institute for Artificial Intelligence in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim,…
HHealth
A blended genome and exome sequencing method captures genetic variation in an unbiased and cost-effective manner
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A blended genome and exome sequencing method captures genetic variation in an unbiased and cost-effective manner

  • July 9, 2026
Ethics approval and consent to participate All cohorts involving human participants that were included in this research have…
SScience
Identifying critical lysines in mammalian histone H3 with high-throughput CRISPR prime editing
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Identifying critical lysines in mammalian histone H3 with high-throughput CRISPR prime editing

  • July 8, 2026
Adapting prime editing for mammalian histone mutagenesis Mouse canonical histone H3 is encoded by nine H3.1 and three…
HHealthcare
The promise of adaptive health in the United Arab Emirates and beyond
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The promise of adaptive health in the United Arab Emirates and beyond

  • June 5, 2026
Department of Medicine, Johns Hopkins University, Baltimore, MD, USA Andrew P. Feinberg Department of Biomedical Engineering, Johns Hopkins…
HHealth
Age distinguishes selection from causation in cancer genomes
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Age distinguishes selection from causation in cancer genomes

  • May 7, 2026
Defining the carcinogenic effect of mutations We defined the carcinogenic effect of a mutation by its influence on…
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